Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 19/20 | 0.62 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15055121 | 0.93 | SCN9A (0.61) | SCN9ASCN5A | |
| SCHEMBL15055347 | 0.91 | SCN9A (0.75) | SCN9ASCN5A | |
| SCHEMBL15055596 | 0.89 | SCN9A (0.61) | SCN9A | |
| SCHEMBL15054825 | 0.87 | SCN9A (0.81) | SCN9ASCN5A | |
| SCHEMBL15055482 | 0.86 | SCN9A (0.60) | SCN9ASCN5A | |
| SCHEMBL15055170 | 0.83 | SCN9A (0.65) | SCN9ASCN5A | |
| SCHEMBL15054776 | 0.82 | SCN9A (0.69) | SCN9A | |
| SCHEMBL15055743 | 0.80 | SCN9A (0.79) | SCN9ASCN5A | |
| SCHEMBL15054785 | 0.80 | SCN9A (0.64) | SCN9ASCN5A | |
| SCHEMBL366854 | 0.80 | SCN9A (0.59) | SCN9ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013093688-A1 | SULFONAMIDE DERIVATIVES AND USE THEREOF AS VGSC INHIBITORS | PFIZER LIMITED (GB) | 2013-06-27 | — | — | WO | claimed |
| WO-2013093688-A1 | SULFONAMIDE DERIVATIVES AND USE THEREOF AS VGSC INHIBITORS | PFIZER LIMITED (GB) | 2013-06-27 | — | — | WO | disclosed |