SCHEMBL150559

SCHEMBL150559

C=CC(=O)NC(C)C(O)(O)O

nearest known ligand 0.60

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.60
CYP2C19 P33261 2/20 0.36
ALDH1A1 P00352 4/20 0.36
MAPK1 P28482 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ACACB O00763 2/20 0.33
TGM2 P21980 1/20 0.31
ZDHHC20 Q5W0Z9 1/20 0.31
ZDHHC2 Q9UIJ5 1/20 0.31
GAA P10253 1/20 0.31
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27673858 0.84 TSHR (0.58) TSHRCYP2C19ALDH1A1MAPK1TDP1
SCHEMBL24772778 0.82 TSHR (0.60) TSHRCYP2C19ALDH1A1MAPK1TDP1
SCHEMBL3978267 0.78 TSHR (0.56) TSHRCYP2C19ALDH1A1MAPK1TDP1
SCHEMBL28091494 0.77 TSHR (0.54) TSHRCYP2C19ALDH1A1MAPK1TDP1
Ammonia Solution, Strong SCHEMBL716083 0.77 TSHR (0.54) TSHRCYP2C19ALDH1A1MAPK1TDP1
Hydrochloric Acid SCHEMBL716084 0.77 TSHR (0.54) TSHRCYP2C19ALDH1A1MAPK1TDP1
SCHEMBL15072 0.75
SCHEMBL27799665 0.75 TSHR (1.00) TSHRCYP2C19ALDH1A1MAPK1TDP1
SCHEMBL636063 0.75 TSHR (0.71) TSHRCYP2C19ALDH1A1MAPK1TDP1
SCHEMBL26479936 0.75 TSHR (0.71) TSHRCYP2C19ALDH1A1MAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9012198-B2 Method for orthopoxvirus production and purification TRANSGENE S.A. (FR) 2015-04-21 US disclosed
US-20140073033-A1 METHOD FOR ORTHOPOXVIRUS PRODUCTION AND PURIFICATION TRANSGENE S.A. (FR) 2014-03-13 US disclosed
US-8609392-B2 Method for orthopoxvirus production and purification TRANSGENE S.A. (FR) 2013-12-17 US disclosed
US-20120190100-A1 ENZYMATIC COMPOSITION FOR THE DIGESTION OF CHICKEN EMBRYOS Transgene AS (FR) 2012-07-26 US disclosed
EP-2456461-A1 ENZYMATIC COMPOSITION FOR THE DIGESTION OF CHICKEN EMBRYOS Transgene SA (FR) 2012-05-30 EP disclosed
EP-2429580-A1 METHOD FOR ORTHOPOXVIRUS PRODUCTION AND PURIFICATION Transgene SA (FR) 2012-03-21 EP disclosed
US-20120058539-A1 METHOD FOR ORTHOPOXVIRUS PRODUCTION AND PURIFICATION TRANSGENE S.A. (FR) 2012-03-08 US disclosed
WO-2011009613-A1 ENZYMATIC COMPOSITION FOR THE DIGESTION OF CHICKEN EMBRYOS TRANSGENE SA (FR) 2011-01-27 WO disclosed
WO-2010130753-A1 METHOD FOR ORTHOPOXVIRUS PRODUCTION AND PURIFICATION TRANSGENE SA (FR) 2010-11-18 WO disclosed
US-7264958-B1 Method for obtaining a purified viral preparation TRANSGENE, S.A. (FR) 2007-09-04 US disclosed