SCHEMBL636063

SCHEMBL636063

C=CC(=O)NC(C)NC(=O)C=C

nearest known ligand 0.71

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.71
ALDH1A1 P00352 5/20 0.42
MAPK1 P28482 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
CYP2C19 P33261 1/20 0.41
ACACB O00763 2/20 0.36
GAA P10253 1/20 0.36
TGM2 P21980 5/20 0.35
ZDHHC20 Q5W0Z9 1/20 0.35
ZDHHC2 Q9UIJ5 1/20 0.35
LMNA P02545 1/20 0.33
FGFR4 P22455 1/20 0.32
GSTO1 P78417 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28518754 0.93 TSHR (0.62) TSHRALDH1A1MAPK1TDP1CYP2C19
SCHEMBL3901758 0.90 TSHR (0.65) TSHRALDH1A1MAPK1TDP1CYP2C19
SCHEMBL5360732 0.87
Hydrochloric Acid SCHEMBL27985636 0.85 TSHR (0.60) TSHRALDH1A1MAPK1TDP1CYP2C19
SCHEMBL6766743 0.85 TSHR (0.54) TSHRALDH1A1MAPK1TDP1CYP2C19
SCHEMBL26479936 0.83 TSHR (0.71) TSHRALDH1A1MAPK1TDP1CYP2C19
SCHEMBL27799665 0.83 TSHR (1.00) TSHRALDH1A1MAPK1TDP1CYP2C19
SCHEMBL15072 0.83
SCHEMBL5693386 0.82 TSHR (0.56) TSHRALDH1A1MAPK1TDP1CYP2C19
Water SCHEMBL23706522 0.81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 422 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025097070-A1 ORAL DOSAGE FORM WITH CATIONICALLY CHARGEABLE HYDROGEL FOR DELIVERY OF ACTIVE AGENT ENTREGA INC. (US) 2025-05-08 WO claimed
CN-117020933-A White pad for semiconductor polishing and production process thereof 安徽禾臣新材料有限公司 2023-11-10 CN claimed
CN-117025115-A Preparation method of adsorption pad for mask plate processing 安徽禾臣新材料有限公司 2023-11-10 CN claimed
CN-117020978-A Preparation method of buffering damping cloth for optical lens processing 安徽禾臣新材料有限公司 2023-11-10 CN claimed
US-20200239680-A1 INTERPENETRATING POLYMER NETWORK CONTAINING CROSS-LINKED POLY(N-VINYLAMINE) KEMIRA OYJ (FI) 2020-07-30 US claimed
US-10584217-B2 Method for producing a material with a network of at least two polymers, a product thereof and use of the product KEMIRA OYJ (FI) 2020-03-10 US claimed
US-10577471-B2 Method for curing curable compositions BASF SE (DE) 2020-03-03 US claimed
US-10189935-B2 Water soluble cross-linked block copolymers KEMIRA OYJ (FI) 2019-01-29 US claimed
US-10174134-B2 Polymer product, method for producing the polymer and use of the polymer KEMIRA OYJ (FI) 2019-01-08 US claimed
EP-3201261-B1 METHOD FOR CURING CURABLE COMPOSITIONS BASF SE (DE) 2018-12-12 EP claimed
US-20020114774-A1 Ionic polymers as toxin-binding agents GELTEX PHARMACEUTICALS, INC. 2002-08-22 US claimed
US-6290947-B1 IN ONE EMBODIMENT, THE POLYMER IS A COPOLYMER COMPRISING A MONOMER HAVING A PENDANT AMMONIUM GROUP AND A HYDROPHOBIC MONOMER. GELTEX PHARMACEUTICALS, INC. 2001-09-18 US claimed
EP-0716606-B1 PHOSPHATE-BINDING POLYMERS FOR ORAL ADMINISTRATION GELTEX PHARMA INC (US) 2001-08-29 EP claimed
US-6264937-B1 MIXTURE WITH LIPASE INHIBITOR GELTEX PHARMACEUTICALS, INC. 2001-07-24 US claimed
US-6203785-B1 ADMINISTERING CROSSLINKED CATIONIC POLYMER ANTICHOLESTEROL AGENTS GELTEX PHARMACEUTICALS, INC. 2001-03-20 US claimed
EP-1043981-A2 FAT-BINDING POLYMERS COMBINED WITH LIPASE INHIBITORS Geltex Pharmaceuticals, Inc. (US) 2000-10-18 EP claimed
US-5925379-A REMOVING BILE SALTS FROM PATIENT BY ADMINISTERING INTERPENETRATING POLYMER NETWORK COMPRISING CATIONIC POLYMER GELTEX PHARMACEUTICALS, INC. (US) 1999-07-20 US claimed
WO-1999034787-A2 FAT-BINDING POLYMERS GELTEX PHARMACEUTICALS, INC. (US) 1999-07-15 WO claimed
WO-1999022743-A1 POLY(DIALLYLAMINE)-BASED PHOSPHATE BINDERS GELTEX PHARMACEUTICALS, INC. (US) 1999-05-14 WO claimed
US-4844889-A FOR HAIR AND SKIN, PROTECTION AGAINST PHOTODEGRADATION L'OREAL (FR) 1989-07-04 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020114774-A1 Ionic polymers as toxin-binding agents PIGS, ANTXR2, MSN TSHR 622/4885ALDH1A1 4693/4885MAPK1 3001/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.