Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 9/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | PDE4A | P27815 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL149392 | 0.85 | PDE10A (0.55) | RAB9ACASP3SENP6SMN1; SMN2MAPT | |
| SCHEMBL147885 | 0.80 | PDE10A (0.75) | RAB9ACASP3SENP6SMN1; SMN2MAPT | |
| SCHEMBL10867414 | 0.79 | RAB9A (0.58) | RAB9ACASP3SENP6SMN1; SMN2MAPT | |
| Dimethylamine SCHEMBL150792 | 0.78 | PDE10A (0.72) | RAB9ACASP3SENP6SMN1; SMN2MAPT | |
| SCHEMBL129052 | 0.78 | PDE10A (0.52) | RAB9ACASP3SENP6SMN1; SMN2MAPT | |
| SCHEMBL129950 | 0.76 | PDE10A (0.58) | RAB9ACASP3SENP6SMN1; SMN2MAPT | |
| SCHEMBL2456041 | 0.76 | RAB9A (0.97) | RAB9ACASP3SENP6SMN1; SMN2MAPT | |
| SCHEMBL147545 | 0.73 | RAB9A (0.44) | RAB9ACASP3SENP6SMN1; SMN2MAPT | |
| SCHEMBL149447 | 0.73 | PDE10A (0.73) | RAB9ASMN1; SMN2MAPTTDP1PDE10A | |
| SCHEMBL151891 | 0.72 | PDE10A (0.55) | RAB9ASMN1; SMN2MAPTTDP1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9227966-B2 | Antimicrobial agents | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-01-05 | — | — | US | disclosed |
| US-20140315939-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2014-10-23 | — | — | US | disclosed |
| US-20120059026-A1 | ANTIMICROBIAL AGENTS | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 2012-03-08 | — | — | US | disclosed |
| WO-2010127307-A1 | ANTIMICROBIAL AGENTS | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2010-11-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120059026-A1 | ANTIMICROBIAL AGENTS | ZYX, Q6ZSR9, ZC3HAV1L | RAB9A 1144/4885CASP3 83/4885SENP6 2656/4885 |
| US-20140315939-A1 | ANTIMICROBIAL AGENTS | ZYX, Q6ZSR9, ZC3HAV1L | RAB9A 964/4885CASP3 82/4885SENP6 2580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.