Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PFKFB3 | Q16875 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.39 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.39 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15056021 | 0.98 | PFKFB3 (0.45) | PFKFB3ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL15055024 | 0.94 | PFKFB3 (0.47) | PFKFB3ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL15055564 | 0.91 | PFKFB3 (0.46) | PFKFB3ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL15055134 | 0.90 | PFKFB3 (0.45) | PFKFB3ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL15055054 | 0.90 | ALDH1A1 (0.46) | PFKFB3ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL15055346 | 0.89 | PFKFB3 (0.45) | PFKFB3ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL15055399 | 0.89 | PFKFB3 (0.47) | PFKFB3ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL15079996 | 0.89 | PFKFB3 (0.46) | PFKFB3ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL15056052 | 0.87 | PFKFB3 (0.57) | PFKFB3ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL15056123 | 0.87 | PFKFB3 (0.49) | PFKFB3ALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2794009-A1 | BISARYLSULFONAMIDES USEFUL IN THE TREATMENT OF INFLAMMATION AND CANCER | Kancera AB (SE) | 2014-10-29 | — | — | EP | disclosed |
| WO-2013093095-A1 | BISARYLSULFONAMIDES USEFUL IN THE TREATMENT OF INFLAMMATION AND CANCER | KANCERA AB (SE) | 2013-06-27 | — | — | WO | disclosed |