Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BUB1 | O43683 | 20/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15056392 | 0.94 | BUB1 (0.69) | BUB1 | |
| SCHEMBL15055841 | 0.92 | BUB1 (0.70) | BUB1 | |
| SCHEMBL15075403 | 0.89 | BUB1 (0.66) | BUB1 | |
| SCHEMBL14853689 | 0.87 | BUB1 (1.00) | BUB1 | |
| SCHEMBL15075377 | 0.85 | BUB1 (0.73) | BUB1 | |
| SCHEMBL15530926 | 0.85 | BUB1 (0.82) | BUB1 | |
| SCHEMBL18899543 | 0.85 | BUB1 (0.70) | BUB1 | |
| SCHEMBL15056247 | 0.84 | BUB1 (0.73) | BUB1 | |
| SCHEMBL14843099 | 0.81 | BUB1 (1.00) | BUB1 | |
| SCHEMBL16713245 | 0.79 | BUB1 (0.77) | BUB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2794596-B1 | SUBSTITUTED BENZYLPYRAZOLES | BAYER IP GMBH (DE) | 2017-05-31 | — | — | EP | claimed |
| US-9643953-B2 | Substituted benzylpyrazoles | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-05-09 | — | — | US | claimed |
| US-9422268-B2 | — | — | 2016-08-23 | — | — | US | claimed |
| EP-2794596-A1 | SUBSTITUTED BENZYLPYRAZOLES | Bayer Intellectual Property GmbH (DE) | 2014-10-29 | — | — | EP | claimed |
| US-20140315934-A1 | SUBSTITUTED BENZYLPYRAZOLES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-10-23 | — | — | US | claimed |
| WO-2013092512-A1 | SUBSTITUTED BENZYLPYRAZOLES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-06-27 | — | — | WO | claimed |
| EP-2794596-B1 | SUBSTITUTED BENZYLPYRAZOLES | BAYER IP GMBH (DE) | 2017-05-31 | — | — | EP | disclosed |
| EP-2794596-B1 | SUBSTITUTED BENZYLPYRAZOLES | BAYER IP GMBH (DE) | 2017-05-31 | — | — | EP | disclosed |
| US-9643953-B2 | Substituted benzylpyrazoles | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-05-09 | — | — | US | disclosed |
| US-9643953-B2 | Substituted benzylpyrazoles | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-05-09 | — | — | US | disclosed |
| US-9643953-B2 | Substituted benzylpyrazoles | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-05-09 | — | — | US | disclosed |
| US-9422268-B2 | — | — | 2016-08-23 | — | — | US | disclosed |
| US-9422268-B2 | — | — | 2016-08-23 | — | — | US | disclosed |
| US-9422268-B2 | — | — | 2016-08-23 | — | — | US | disclosed |
| EP-2794596-A1 | SUBSTITUTED BENZYLPYRAZOLES | Bayer Intellectual Property GmbH (DE) | 2014-10-29 | — | — | EP | disclosed |
| US-20140315934-A1 | SUBSTITUTED BENZYLPYRAZOLES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-10-23 | — | — | US | disclosed |
| US-20140315934-A1 | SUBSTITUTED BENZYLPYRAZOLES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-10-23 | — | — | US | disclosed |
| US-20140315934-A1 | SUBSTITUTED BENZYLPYRAZOLES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-10-23 | — | — | US | disclosed |
| WO-2013092512-A1 | SUBSTITUTED BENZYLPYRAZOLES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-06-27 | — | — | WO | disclosed |
| WO-2013092512-A1 | SUBSTITUTED BENZYLPYRAZOLES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140315934-A1 | SUBSTITUTED BENZYLPYRAZOLES | CYP3A43, CYP3A7, ABCB1 | BUB1 2233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.