Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | TNKS | O95271 | 3/20 | 0.48 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9427449 | 0.85 | SLC6A4 (0.58) | POLBKMT2ASLC6A4SLC6A3SLC6A2 | |
| SCHEMBL16298335 | 0.84 | SLC6A4 (0.66) | POLBSLC6A4SLC6A3SLC6A2 | |
| SCHEMBL31525724 | 0.82 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1POLBSMN1; SMN2LMNA | |
| SCHEMBL2489568 | 0.81 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1POLBSMN1; SMN2LMNA | |
| SCHEMBL17789554 | 0.80 | SLC6A4 (0.69) | ALDH1A1L3MBTL1SMN1; SMN2LMNAHTT | |
| SCHEMBL3271078 | 0.78 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1POLBSMN1; SMN2LMNA | |
| SCHEMBL21964990 | 0.77 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1POLBSMN1; SMN2LMNA | |
| SCHEMBL15057117 | 0.76 | ALDH1A1 (0.78) | ALDH1A1L3MBTL1POLBSMN1; SMN2LMNA | |
| SCHEMBL15075064 | 0.76 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1POLBSMN1; SMN2LMNA | |
| SCHEMBL3270654 | 0.76 | HRH3 (0.60) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013093508-A2 | WNT PATHWAY INHIBITORS | OSLO UNIVERSITY HOSPITAL HF (NO) | 2013-06-27 | — | — | WO | disclosed |