SCHEMBL150582

SCHEMBL150582

C=C(C)C(=O)OCC(C)(C)N

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.47
THRB P10828 1/20 0.44
ALDH1A1 P00352 2/20 0.41
TDP1 Q9NUW8 2/20 0.35
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
HTT P42858 1/20 0.33
LMNA P02545 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chloromethane SCHEMBL7203982 0.98 TSHR (0.45) TSHRTHRBALDH1A1TDP1POLB
Hydrochloric Acid SCHEMBL7877858 0.98 TSHR (0.45) TSHRTHRBALDH1A1TDP1POLB
Ammonia Solution, Strong SCHEMBL27914280 0.98 TSHR (0.45) TSHRTHRBALDH1A1TDP1POLB
Acrylamide SCHEMBL4655069 0.89 TSHR (0.39) TSHRTHRBALDH1A1TDP1LMNA
SCHEMBL18861982 0.84 TSHR (0.41) TSHRTHRBALDH1A1TDP1
SCHEMBL3957681 0.83 TSHR (0.44) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL28851496 0.83 LMNA (0.31) LMNAHSD17B10
Hydrochloric Acid SCHEMBL4057513 0.83 TSHR (0.47) TSHRTHRBALDH1A1TDP1POLB
Hydrochloric Acid SCHEMBL4057509 0.83 TSHR (0.47) TSHRTHRBALDH1A1TDP1POLB
SCHEMBL51592 0.82 TSHR (0.50) TSHRTHRBALDH1A1TDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 675 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12042994-B2 Sustainable additive manufacturing resins and methods of recycling CARBON, INC. (US) 2024-07-23 US claimed
EP-4257119-A1 OLAPARIB SOLID DISPERSION COMPOSITION WITH IMPROVED STABILITY AND BIOAVAILABILITY Samyang Holdings Corporation (KR) 2023-10-11 EP claimed
CN-113000835-A Core-shell liquid metal nano-particles and method for preparing same by using power ultrasound 西北工业大学 2021-06-22 CN claimed
EP-3004033-B1 METHOD FOR PURIFICATION OF 18F-LABELED CHOLINE ANALOGUES TRASIS S A (BE) 2019-05-08 EP claimed
US-9839702-B2 Method for purification of 18F-labeled choline analogues TRASIS S.A. (BE) 2017-12-12 US claimed
EP-2148836-B1 METHOD FOR THE PREPARATION OF REACTIVE [18]F FLUORIDE TRASIS S A (BE) 2017-10-25 EP claimed
US-9763879-B2 Oral film containing opiate enteric-release beads LTS LOHMANN THERAPIE-SYSTEME AG (DE) 2017-09-19 US claimed
US-9687445-B2 Oral film containing opiate enteric-release beads LTS LOHMANN THERAPIE-SYSTEME AG (DE) 2017-06-27 US claimed
CN-101744676-B Adhesion promoting primer for coated surface CORDIS CORP. (US) 2016-12-14 CN claimed
CN-104602684-B The pharmaceutical composition of the multi-layer coated form of the oral administration containing omega-3 fatty acid or its Arrcostab and statins 健制药株式会社 2016-08-17 CN claimed
EP-0952770-A4 SYSTEM FOR RENDERING SUBSTANTIALLY NON-DISSOLUBLE BIO-AFFECTING AGENTS BIO-AVAILABLE FUISZ TECHNOLOGIES LTD (US) 1999-12-22 EP claimed
EP-0952770-A1 SYSTEM FOR RENDERING SUBSTANTIALLY NON-DISSOLUBLE BIO-AFFECTING AGENTS BIO-AVAILABLE FUISZ TECHNOLOGIES LTD. (US) 1999-11-03 EP claimed
US-5695925-A AMPHOTERIC POLYMER CONSISTS OF CO-OR TERPOLYMER OF ACRYLIC ACID, METHACYLATE AND N,N-DIMETHYL-AMINOETHYL METHACRYLATE IS IMMOBILIZED ON THE SURFACE OF ACOUSTIC SENSOR, CAPABLE OF DETECTING CHANGE OF SURFACE PROPOGATION E. I. DU PONT DE NEMOURS AND COMPANY (US) 1997-12-09 US claimed
WO-1997008950-A1 SYSTEM FOR RENDERING SUBSTANTIALLY NON-DISSOLUBLE BIO-AFFECTING AGENTS BIO-AVAILABLE FUISZ TECHNOLOGIES, LTD. (US) 1997-03-13 WO claimed
EP-0583319-B1 LIPASE-CATALYZED ESTER HYDROLYSIS NOVO NORDISK AS (DK) 1995-07-12 EP claimed
EP-0576598-A1 HAIR CARE COMPOSITIONS HAVING STYLING/CONDITIONING AGENT AND PLASTICIZER THE PROCTER & GAMBLE COMPANY (US) 1994-01-05 EP claimed
WO-1993009867-A1 PROCESS FOR COATING SMALL PARTICLES USING A ROTOR FLUIDIZED BED APPARATUS WARNER-LAMBERT COMPANY (US) 1993-05-27 WO claimed
EP-0270249-A2 Hair fixative composition containing cationic organic polymer and polydiorganosiloxane microemulsions DOW CORNING CORPORATION (US) 1988-06-08 EP claimed
US-4415644-A PARTICLES FORMED BY SUSPENSION POLYMERIZATION IN THE PRESENCE OF A DEMULSIFIER; HIGH DENSITY KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1983-11-15 US claimed
US-4403070-A COPOLYMER OF METHYL METHACRYLATE, DIMETHYLAMINOETHYL METHACRYLATE, AND OCTADECYL METHACRYLATE MADRANGE ANNIE (FR) 1983-09-06 US claimed