Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 2/20 | 0.49 |
| ▸ | NR1H2 | P55055 | 13/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 11/20 | 0.33 |
| ▸ | PPARD | Q03181 | 3/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4894574 | 0.85 | VDR (0.66) | VDRNR1H2NR1H3PPARDPPARG | |
| SCHEMBL4881083 | 0.84 | VDR (0.61) | VDRNR1H2NR1H3PPARDPPARG | |
| SCHEMBL4617119 | 0.80 | VDR (0.75) | VDR | |
| SCHEMBL27587233 | 0.80 | VDR (0.48) | VDRPPARDFFAR1 | |
| SCHEMBL4884277 | 0.77 | VDR (0.79) | VDRNR1H2NR1H3PGRRORC | |
| SCHEMBL27568056 | 0.77 | VDR (0.44) | VDRPPARDPPARAFFAR1 | |
| SCHEMBL6576788 | 0.76 | VDR (0.76) | VDRNR1H2NR1H3PGRRORC | |
| SCHEMBL4891356 | 0.75 | VDR (0.73) | VDRNR1H2NR1H3PGRRORC | |
| SCHEMBL2641441 | 0.74 | VDR (0.84) | VDRPPARDPPARGPPARAFFAR1 | |
| SCHEMBL4881104 | 0.72 | VDR (0.77) | VDRPPARDPPARGPPARAFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013092936-A2 | USE OF 5-AMINOLEVULINIC ACID AND ESTERS, IN COMBINATION WITH A VITAMIN D DERIVATIVE OR ANALOG IN PHOTOCHEMOTHERAPY, AND THEIR USES IN TREATING ACNE | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2013-06-27 | — | — | WO | claimed |
| WO-2013092936-A2 | USE OF 5-AMINOLEVULINIC ACID AND ESTERS, IN COMBINATION WITH A VITAMIN D DERIVATIVE OR ANALOG IN PHOTOCHEMOTHERAPY, AND THEIR USES IN TREATING ACNE | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2013-06-27 | — | — | WO | disclosed |