Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10015620 | 0.82 | SMN1; SMN2 (0.30) | SMN1; SMN2 | |
| SCHEMBL16726716 | 0.82 | SMN1; SMN2 (0.30) | SMN1; SMN2 | |
| SCHEMBL1991587 | 0.78 | HMGCR (0.31) | — | |
| SCHEMBL18855273 | 0.76 | SMN1; SMN2 (0.43) | SMN1; SMN2THRBALOX15 | |
| SCHEMBL10046539 | 0.73 | SMN1; SMN2 (0.34) | SMN1; SMN2 | |
| SCHEMBL13922064 | 0.71 | THRB (0.31) | THRBALOX15 | |
| SCHEMBL6800910 | 0.69 | THRB (0.33) | THRBALOX15 | |
| SCHEMBL14546385 | 0.65 | TSHR (0.36) | SMN1; SMN2 | |
| SCHEMBL2217512 | 0.64 | THRB (0.41) | SMN1; SMN2THRBALOX15 | |
| SCHEMBL10326025 | 0.64 | THRB (0.41) | SMN1; SMN2THRBALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8471045-B2 | Synthesis of statins | LEK PHARMACEUTICALS D.D. (SI) | 2013-06-25 | — | — | US | disclosed |