Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | IDUA | P35475 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 3/20 | 0.30 |
| ▸ | CA9 | Q16790 | 2/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18911637 | 1.00 | SUCNR1 (0.39) | SUCNR1THRBLMNATDP1IDUA | |
| SCHEMBL12346259 | 1.00 | SUCNR1 (0.39) | SUCNR1THRBLMNATDP1IDUA | |
| SCHEMBL13618641 | 1.00 | SUCNR1 (0.39) | SUCNR1THRBLMNATDP1IDUA | |
| SCHEMBL1669031 | 1.00 | SUCNR1 (0.39) | SUCNR1THRBLMNATDP1IDUA | |
| SCHEMBL24212766 | 1.00 | SUCNR1 (0.39) | SUCNR1THRBLMNATDP1IDUA | |
| SCHEMBL4267050 | 1.00 | SUCNR1 (0.39) | SUCNR1THRBLMNATDP1IDUA | |
| SCHEMBL23720424 | 1.00 | SUCNR1 (0.39) | SUCNR1THRBLMNATDP1IDUA | |
| SCHEMBL13792996 | 1.00 | SUCNR1 (0.39) | SUCNR1THRBLMNATDP1IDUA | |
| SCHEMBL21097517 | 1.00 | SUCNR1 (0.39) | SUCNR1THRBLMNATDP1IDUA | |
| SCHEMBL17828572 | 1.00 | SUCNR1 (0.39) | SUCNR1THRBLMNATDP1IDUA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8470786-B2 | Pyrroloquinolinyl-pyrrolidine-2,5-dione compositions and methods for preparing and using same | ARQULE, INC. (US) | 2013-06-25 | — | — | US | disclosed |