SCHEMBL1669031

SCHEMBL1669031

O=C(O)C1OCC(O)C(O)C1O

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ SUCNR1 Q9BXA5 1/20 0.39
▸ THRB P10828 1/20 0.38
▸ LMNA P02545 1/20 0.38
▸ TDP1 Q9NUW8 1/20 0.37
▸ IDUA P35475 1/20 0.35
▸ CA1 P00915 3/20 0.30
▸ CA9 Q16790 2/20 0.30
▸ CA2 P00918 1/20 0.30
▸ KDM4E B2RXH2 1/20 0.30
▸ ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18911637 1.00 SUCNR1 (0.39) SUCNR1THRBLMNATDP1IDUA
SCHEMBL12346259 1.00 SUCNR1 (0.39) SUCNR1THRBLMNATDP1IDUA
SCHEMBL13618641 1.00 SUCNR1 (0.39) SUCNR1THRBLMNATDP1IDUA
SCHEMBL24212766 1.00 SUCNR1 (0.39) SUCNR1THRBLMNATDP1IDUA
SCHEMBL4267050 1.00 SUCNR1 (0.39) SUCNR1THRBLMNATDP1IDUA
SCHEMBL23720424 1.00 SUCNR1 (0.39) SUCNR1THRBLMNATDP1IDUA
SCHEMBL13792996 1.00 SUCNR1 (0.39) SUCNR1THRBLMNATDP1IDUA
SCHEMBL15061094 1.00 SUCNR1 (0.39) SUCNR1THRBLMNATDP1IDUA
SCHEMBL21097517 1.00 SUCNR1 (0.39) SUCNR1THRBLMNATDP1IDUA
SCHEMBL17828572 1.00 SUCNR1 (0.39) SUCNR1THRBLMNATDP1IDUA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 278 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709714-A1 SUBSTITUTED QUINOXALINES Mirati Therapeutics, Inc. (US) 2026-03-18 — — EP claimed
US-20260027103-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING A QUINOLONE COMPOUND FOR IRRITABLE BOWEL SYNDROME OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2026-01-29 — — US claimed
US-20250325676-A1 CAMPTOTHECIN PRODRUG AND PHARMACEUTICAL COMPOSITION THEREOF TIANJIN HEMAY ONCOLOGY PHARMACEUTICAL CO LTD (CN) 2025-10-23 — — US claimed
EP-4554588-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING A QUINOLONE COMPOUND FOR IRRITABLE BOWEL SYNDROME Otsuka Pharmaceutical Co., Ltd. (JP) 2025-05-21 — — EP claimed
CN-119451970-A N-substituted indole derivatives and conjugates thereof for the treatment of cancer 埃维克斯塔生物公司 2025-02-14 — — CN claimed
CN-119343138-A Pharmaceutical composition for irritable bowel syndrome comprising quinolone compounds 大塚制药株式会社 2025-01-21 — — CN claimed
CN-119212997-A Indazoles as inhibitors of hematopoietic progenitor kinase 1 (HPK 1) and methods of use thereof 第一生物治疗股份有限公司 2024-12-27 — — CN claimed
WO-2024238221-A1 SUBSTITUTED QUINOXALINES Mirati Therapeutics, Inc. (US) 2024-11-21 — — WO claimed
WO-2024012421-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING A QUINOLONE COMPOUND FOR IRRITABLE BOWEL SYNDROME OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2024-01-18 — — WO claimed
CN-117263999-A Camptothecin prodrugs and pharmaceutical compositions thereof 天津和美奥康医药科技有限公司 2023-12-22 — — CN claimed
CN-111278821-B Spiro compounds as farnesol X receptor modulators 百时美施贵宝公司 2023-10-03 — — CN claimed
CN-111278817-B Polycyclic compounds as farnesol X receptor modulators 百时美施贵宝公司 2023-05-16 — — CN claimed
WO-2023277656-A1 NOVEL BENZOPYRAN DERIVATIVE AND USE THEREOF (주)스파크바이오파마 2023-01-05 — — WO claimed
CN-115038445-A Novel medicaments for the treatment of inflammatory diseases 大塚制药株式会社 2022-09-09 — — CN claimed
CN-114929224-A Novel medicine for treating hepatic encephalopathy 大塚制药株式会社 2022-08-19 — — CN claimed
WO-2022048529-A1 FORSYTHIAE FRUCTUS COMPONENT AND OPTIONAL GINSENG COMPONENT, AND USE THEREOF 大连富生天然药物开发有限公司 2022-03-10 — — WO claimed
WO-2018165250-A1 GLUCURONIDE PRODRUGS OF TOFACITINIB THERAVANCE BIOPHARMA R&D IP, LLC (US) 2018-09-13 — — WO claimed
US-20070004774-A1 Cept inhibitors and metabolites thereof PFIZER INC. 2007-01-04 — — US claimed
EP-1670765-A2 CETP INHIBITORS AND METABOLITES THEREOF Pfizer Products Inc. (US) 2006-06-21 — — EP claimed
WO-2005033082-A2 CETP INHIBITORS AND METABOLITES THEREOF PFIZER PRODUCTS INC. (US) 2005-04-14 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070004774-A1 Cept inhibitors and metabolites thereof CETP, LCAT, MTTP SUCNR1 2230/4885THRB 280/4885LMNA 1724/4885
US-20260027103-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING A QUINOLONE COMPOUND FOR IRRITABLE BOWEL SYNDROME SI, VIP, SLC10A2 SUCNR1 21/4885THRB 3831/4885LMNA 3350/4885
US-20250325676-A1 CAMPTOTHECIN PRODRUG AND PHARMACEUTICAL COMPOSITION THEREOF TOP2B, PDE10A, REV1 SUCNR1 1132/4885THRB 946/4885LMNA 2309/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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