Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.45 |
| ▸ | DRD3 | P35462 | 3/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | MLNR | O43193 | 1/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | PANK3 | Q9H999 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4693057 | 0.99 | KMT2A (0.52) | KMT2AGAAMEN1KDM4EDRD2 | |
| SCHEMBL15061389 | 0.93 | KMT2A (0.53) | KMT2AGAAMEN1KDM4EDRD2 | |
| SCHEMBL4688586 | 0.93 | KMT2A (0.53) | KMT2AGAAMEN1KDM4EDRD2 | |
| Hydrochloric Acid SCHEMBL4692989 | 0.92 | KMT2A (0.52) | KMT2AGAAMEN1KDM4EDRD2 | |
| SCHEMBL15061305 | 0.89 | KMT2A (0.49) | KMT2AGAAMEN1KDM4EDRD2 | |
| SCHEMBL4690903 | 0.89 | KMT2A (0.49) | KMT2AGAAMEN1KDM4EDRD2 | |
| SCHEMBL4690184 | 0.88 | DRD2 (0.44) | KMT2AKDM4EDRD2DRD3KCNH2 | |
| SCHEMBL4690178 | 0.88 | DRD2 (0.44) | KMT2AKDM4EDRD2DRD3KCNH2 | |
| Hydrochloric Acid SCHEMBL4688529 | 0.88 | KMT2A (0.48) | KMT2AGAAMEN1KDM4EDRD2 | |
| Hydrochloric Acid SCHEMBL27635996 | 0.87 | DRD2 (0.43) | KMT2AKDM4EDRD2DRD3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476275-B2 | N-[piperazinyl hetaryl]arylsufonamide compounds with affinity for the dopamine D3 receptor | ABBOTT GMBH & CO. KG (DE) | 2013-07-02 | — | — | US | claimed |