Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR2 | Q969V1 | 3/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | RBP4 | P02753 | 1/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10092817 | 0.81 | MCHR2 (0.50) | MCHR2SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL381500 | 0.81 | KDM1A (0.52) | MCHR2KDM1A | |
| SCHEMBL29993455 | 0.81 | KDM1A (0.52) | MCHR2KDM1A | |
| SCHEMBL6968834 | 0.81 | KDM1A (0.52) | MCHR2KDM1A | |
| SCHEMBL6970469 | 0.81 | KDM1A (0.52) | MCHR2KDM1A | |
| SCHEMBL6959970 | 0.81 | KDM1A (0.52) | MCHR2KDM1A | |
| SCHEMBL26116066 | 0.77 | MCHR2 (0.48) | MCHR2SIGMAR1HTR2AHTR2CHTR2B | |
| SCHEMBL13510926 | 0.76 | MEN1 (0.56) | — | |
| SCHEMBL379939 | 0.76 | SIGMAR1 (0.37) | SIGMAR1HTR2AHTR2CHTR2BGRIN2D | |
| SCHEMBL379938 | 0.76 | SIGMAR1 (0.37) | SIGMAR1HTR2AHTR2CHTR2BGRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476253-B2 | Amide derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2013-07-02 | — | — | US | disclosed |