Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9403737 | 1.00 | PDE4A (0.43) | PDE4ATSHRCYP2C9PAX8ALDH1A1 | |
| SCHEMBL2263460 | 1.00 | PDE4A (0.43) | PDE4ATSHRCYP2C9PAX8ALDH1A1 | |
| SCHEMBL3190386 | 1.00 | PDE4A (0.43) | PDE4ATSHRCYP2C9PAX8ALDH1A1 | |
| SCHEMBL7155653 | 1.00 | PDE4A (0.43) | PDE4ATSHRCYP2C9PAX8ALDH1A1 | |
| SCHEMBL3433527 | 1.00 | PDE4A (0.43) | PDE4ATSHRCYP2C9PAX8ALDH1A1 | |
| SCHEMBL208916 | 1.00 | PDE4A (0.43) | PDE4ATSHRCYP2C9PAX8ALDH1A1 | |
| SCHEMBL7149416 | 1.00 | PDE4A (0.43) | PDE4ATSHRCYP2C9PAX8ALDH1A1 | |
| SCHEMBL7150290 | 1.00 | PDE4A (0.43) | PDE4ATSHRCYP2C9PAX8ALDH1A1 | |
| SCHEMBL17867251 | 0.86 | TSHR (0.41) | PDE4ATSHRCYP2C9PAX8ALDH1A1 | |
| SCHEMBL17867373 | 0.86 | TSHR (0.41) | PDE4ATSHRCYP2C9PAX8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019055971-A2 | MULTIPLEX ENTERIC ASSAY AND METHODS OF USE THEREOF | CARRERA BIOSCIENCE INC. (US) | 2019-03-21 | — | — | WO | disclosed |
| US-9333251-B2 | Vaccine for protection against Shigella sonnei disease | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2016-05-10 | — | — | US | disclosed |
| US-20150182611-A1 | VACCINE FOR PROTECTION AGAINST SHIGELLA SONNEI DISEASE | US HEALTH (US) | 2015-07-02 | — | — | US | disclosed |
| US-8992943-B2 | Vaccine for protection against Shigella sonnei disease | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2015-03-31 | — | — | US | disclosed |
| US-20130078278-A1 | VACCINE FOR PROTECTION AGAINST SHIGELLA SONNEI DISEASE | GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY (US) | 2013-03-28 | — | — | US | disclosed |
| US-8337832-B2 | Vaccine for protection against Shigella sonnei disease | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2012-12-25 | — | — | US | disclosed |
| US-20120058142-A1 | VACCINE FOR PROTECTION AGAINST SHIGELLA SONNEI DISEASE | Government of The United States of America, as represented by the The Secretary (US) | 2012-03-08 | — | — | US | disclosed |
| US-20100272748-A1 | VACCINE FOR PROTECTION AGAINST SHIGELLA SONNEI DISEASE | THE GOVERNMENT OF THE U.S.A., AS REPRESENTED BY SECRETARY OF HEALTH AND HUMAN SERVICES (US) | 2010-10-28 | — | — | US | disclosed |
| US-7541043-B2 | antigen is expressed from Salmonella enterica serovar Typhi strain Ty21a; gene cluster operably linked to transcriptional promoter and termination signals; for protecting the host against bacillary dysentery and shigellosis; immunotherapy | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2009-06-02 | — | — | US | disclosed |
| US-20050281841-A1 | antigen is expressed from Salmonella enterica serovar Typhi strain Ty21a; gene cluster operably linked to transcriptional promoter and termination signals; for protecting the host against bacillary dysentery and shigellosis; immunotherapy | THE GOVERNMENT OF THE U.S. AS REPRESENTED BY THE SECRETARY OF HEALTH AND HUMAN SERVICES | 2005-12-22 | — | — | US | disclosed |