⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11070691 | 0.73 | — | — | |
| SCHEMBL7977394 | 0.73 | — | — | |
| SCHEMBL8362969 | 0.73 | — | — | |
| SCHEMBL23130488 | 0.69 | — | — | |
| SCHEMBL15587849 | 0.69 | — | — | |
| SCHEMBL16302096 | 0.69 | — | — | |
| SCHEMBL19120410 | 0.69 | — | — | |
| SCHEMBL13920325 | 0.69 | — | — | |
| SCHEMBL18768264 | 0.69 | — | — | |
| SCHEMBL13551029 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8470850-B2 | Inhibitors of VEGF receptor and HGF receptor signalling | METHYLGENE INC. (CA) | 2013-06-25 | — | — | US | disclosed |