⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11070691 | 1.00 | — | — | |
| SCHEMBL19156417 | 0.78 | — | — | |
| SCHEMBL14496823 | 0.78 | — | — | |
| SCHEMBL22944732 | 0.76 | — | — | |
| SCHEMBL13920325 | 0.73 | — | — | |
| SCHEMBL15061676 | 0.73 | — | — | |
| SCHEMBL16193068 | 0.73 | — | — | |
| SCHEMBL18768264 | 0.73 | — | — | |
| SCHEMBL13551029 | 0.73 | — | — | |
| SCHEMBL16204327 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357181-A1 | METHODS AND COMPOUNDS USEFUL IN THE SYTHESIS OF AN AAK1 INHIBITOR | LEXICON PHARMACEUTICALS, INC. | 2023-11-09 | — | — | US | disclosed |
| US-20230339982-A1 | CHEMICAL COMPOUND, USE OF AT LEAST ONE SUCH CHEMICAL COMPOUND IN AN OPTOELECTRONIC COMPONENT, AND OPTOELECTRONIC COMPONENT CONTAINING AT LEAST ONE SUCH CHEMICAL COMPOUND | TECHNISCHE UNIVERSITAET DRESDEN (DE) | 2023-10-26 | — | — | US | disclosed |
| WO-2021087093-A1 | SMALL MOLECULE DEGRADERS OF HELIOS AND METHODS OF USE | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2021-05-06 | — | — | WO | disclosed |
| WO-2021055630-A1 | SUBSTITUTED, SATURATED AND UNSATURATED N-HETEROCYCLIC CARBOXAMIDES AND RELATED COMPOUNDS FOR THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS | BIAL- BIOTECH INVESTMENTS, INC. (US) | 2021-03-25 | — | — | WO | disclosed |
| US-20210061810-A1 | PYRIMIDO[4,5-D]PYRIMIDIN-2-ONE DERIVATIVES AS PROTEIN KINASE INHIBITORS | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2021-03-04 | — | — | US | disclosed |
| WO-2017191599-A1 | SUBSTITUTED 2, 4-DIAMINO-QUINOLINE DERIVATIVES FOR USE IN THE TREATMENT OF PROLIFERATIVE DISEASES | GENOSCIENCE PHARMA (FR) | 2017-11-09 | — | — | WO | disclosed |
| EP-2688403-B1 | OPIOID RECEPTOR LIGANDS AND METHODS OF USING AND MAKING SAME | TREVENA INC (US) | 2017-05-31 | — | — | EP | disclosed |
| EP-3168847-A1 | PHOTOELECTRIC CONVERSION ELEMENT, DYE-SENSITIZED SOLAR CELL, METAL COMPLEX DYE, DYE SOLUTION, AND TERPYRIDINE COMPOUND OR ESTERIFICATION PRODUCT THEREOF | Fujifilm Corporation (JP) | 2017-05-17 | — | — | EP | disclosed |
| EP-2078003-B1 | ANILINOPIPERAZINE DERIVATIVES AND METHODS OF USE THEREOF | MERCK SHARP & DOHME (US) | 2017-03-08 | — | — | EP | disclosed |
| EP-1905829-B1 | Templated molecules and methods for using such molecules | NUEVOLUTION AS (DK) | 2016-02-17 | — | — | EP | disclosed |
| EP-1479397-B1 | 2,4,6-TRIAMINO-1,3,5-TRIAZINE DERIVATIVE | ASTELLAS PHARMA INC (JP) | 2011-06-08 | — | — | EP | disclosed |
| WO-2010005534-A2 | PROTEASOME INHIBITORS FOR SELECTIVELY INDUCING APOPTOSIS IN CANCER CELLS | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. (US) | 2010-01-14 | — | — | WO | disclosed |
| US-20030153754-A1 | Fused pyrrolecarboxamides; a new class of GABA brain receptor ligands | NEUROGEN CORPORATION, A CORPORATION OF THE STATE OF DELAWARE | 2003-08-14 | — | — | US | disclosed |
| US-4487947-A | POLYAMIDES, CURING AGENTS, EPOXY RESINS | CIBA-GEIGY CORPORATION (US) | 1984-12-11 | — | — | US | disclosed |
| US-4484004-A | CURING AGENT FOR EPOXY RESIN AND POLYAMIDES | CIBA-GEIGY CORPORATION (US) | 1984-11-20 | — | — | US | disclosed |
| US-4460790-A | PRODUCING POLYAMIDES, CURING AGENTS FOR EPOXIDE RESINS | CIBA-GEIGY CORPORATION (US) | 1984-07-17 | — | — | US | disclosed |
| US-4355177-A | Substituted 11-amino-undeca-4,8-dienal and 11-amino-undecanal derivatives and processes for their preparation | CIBA-GEIGY CORPORATION (US) | 1982-10-19 | — | — | US | disclosed |
| US-4332969-A | Substituted 11-aminoundecanols | CIBA-GEIGY CORPORATION (US) | 1982-06-01 | — | — | US | disclosed |
| US-4277621-A | OXIMES AND HYDRAZONES; INTERMEDIATES FOR DIAMINES FOR POLYAMIDES OR CURING EPOXY RESINS | CIBA-GEIGY CORPORATION (US) | 1981-07-07 | — | — | US | disclosed |
| US-4213901-A | PESTICIDES | CIBA-GEIGY CORPORATION (US) | 1980-07-22 | — | — | US | disclosed |