Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 2/20 | 0.32 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15062057 | 0.81 | — | — | |
| SCHEMBL10638515 | 0.66 | TRIM24 (0.47) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL18642871 | 0.64 | TRIM24 (0.50) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL18642898 | 0.61 | TRIM24 (0.47) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL10260449 | 0.61 | TRIM24 (0.41) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL6250876 | 0.61 | TRIM24 (0.35) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL4618953 | 0.60 | TRIM24 (0.57) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL4620542 | 0.60 | TRIM24 (0.57) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL33935 | 0.58 | — | — | |
| SCHEMBL17971494 | 0.58 | TRIM24 (0.54) | TRIM24TRIM33ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013093220-A1 | METHOD FOR SYNTHESISING IVABRADINE AND THE PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF | LES LABORATOIRES SERVIER (FR) | 2013-06-27 | — | — | WO | disclosed |
| EP-2607353-A1 | New method for synthesising ivabradine and its added salts with a pharmaceutically acceptable acid. | Les Laboratoires Servier (FR) | 2013-06-26 | — | — | EP | disclosed |