⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15062064 | 0.81 | TRIM24 (0.32) | — | |
| SCHEMBL15044227 | 0.81 | TRIM24 (0.32) | — | |
| SCHEMBL15044262 | 0.74 | — | — | |
| SCHEMBL10638515 | 0.57 | TRIM24 (0.47) | — | |
| SCHEMBL18642871 | 0.54 | TRIM24 (0.50) | — | |
| SCHEMBL18642898 | 0.52 | TRIM24 (0.47) | — | |
| SCHEMBL6250876 | 0.52 | TRIM24 (0.35) | — | |
| SCHEMBL40325 | 0.51 | TRIM24 (0.39) | — | |
| SCHEMBL4309011 | 0.51 | TRIM24 (0.39) | — | |
| SCHEMBL6666733 | 0.49 | TRIM24 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013093220-A1 | METHOD FOR SYNTHESISING IVABRADINE AND THE PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF | LES LABORATOIRES SERVIER (FR) | 2013-06-27 | — | — | WO | disclosed |
| EP-2607353-A1 | New method for synthesising ivabradine and its added salts with a pharmaceutically acceptable acid. | Les Laboratoires Servier (FR) | 2013-06-26 | — | — | EP | disclosed |