Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 6/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 6/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL837536 | 0.83 | CHRNB2 (0.56) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL10401636 | 0.81 | CHRNB2 (0.54) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL12780602 | 0.80 | CHRNB2 (0.54) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL16541245 | 0.77 | CHRNB2 (0.65) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL21814500 | 0.76 | CHRNB2 (0.49) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL16024869 | 0.76 | CHRNB2 (0.49) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL18967264 | 0.76 | — | — | |
| SCHEMBL15211959 | 0.75 | EPHX1 (0.57) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL12193523 | 0.75 | CHRNB2 (0.47) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL17551415 | 0.75 | CHRNB2 (0.47) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1608369-B1 | USE OF ORGANIC COMPOUNDS FOR IMMUNOPOTENTIATION | NOVARTIS VACCINES & DIAGNOSTIC (US) | 2013-06-26 | — | — | EP | disclosed |