SCHEMBL15062099

SCHEMBL15062099

CN1C(=O)CN(I)CC1=O

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 2/20 0.32
GSK3B P49841 2/20 0.32
CRBN Q96SW2 1/20 0.31
BRD4 O60885 1/20 0.31
BRD2 P25440 1/20 0.31
TSHR P16473 1/20 0.31
MGLL Q99685 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL84388 0.75 GSK3A (0.35) GSK3AGSK3BCRBNBRD4BRD2
SCHEMBL3333138 0.71 PIK3CD (0.40) GSK3AGSK3BCRBNBRD4BRD2
SCHEMBL18512330 0.70
SCHEMBL27941 0.67
SCHEMBL7945735 0.67
SCHEMBL23894741 0.67 GSK3A (0.38) GSK3AGSK3BCRBNBRD4BRD2
SCHEMBL9020270 0.67
SCHEMBL1101969 0.67 ALDH1A1 (0.33) GSK3AGSK3BTSHR
SCHEMBL12208456 0.67 PIK3CD (0.38) GSK3AGSK3B
SCHEMBL21166239 0.67 KDM4E (0.32) GSK3AGSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1608369-B1 USE OF ORGANIC COMPOUNDS FOR IMMUNOPOTENTIATION NOVARTIS VACCINES & DIAGNOSTIC (US) 2013-06-26 EP disclosed