SCHEMBL15062325

SCHEMBL15062325

COC(=O)/C=C\CCC#C/C(C)=C(/C)C#CCC/C=C\C(=O)OC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 2/20 0.43
KEAP1 Q14145 1/20 0.43
NFE2L2 Q16236 1/20 0.43
ALDH1A1 P00352 3/20 0.33
MAPT P10636 2/20 0.33
ALOX15 P16050 1/20 0.33
RECQL P46063 1/20 0.33
HSD17B10 Q99714 1/20 0.33
KDM4E B2RXH2 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
TTR P02766 1/20 0.31
APP P05067 1/20 0.31
POLB P06746 1/20 0.31
RAB9A P51151 1/20 0.31
GFPT1 Q06210 1/20 0.30
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
TYR P14679 1/20 0.30
CA7 P43166 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12133295 0.79 HCAR2 (0.40) HCAR2KEAP1NFE2L2MAPTPOLB
SCHEMBL14549038 0.79 HCAR2 (0.40) HCAR2KEAP1NFE2L2MAPT
SCHEMBL12134339 0.77 HCAR2 (0.39) HCAR2KEAP1NFE2L2MAPTTTR
SCHEMBL14553218 0.77 HCAR2 (0.39) HCAR2KEAP1NFE2L2MAPTTTR
SCHEMBL4799716 0.77 HCAR2 (0.46) HCAR2KEAP1NFE2L2ALDH1A1MAPT
SCHEMBL4799720 0.77 HCAR2 (0.46) HCAR2KEAP1NFE2L2ALDH1A1MAPT
SCHEMBL1353542 0.75 HCAR2 (0.36) HCAR2KEAP1NFE2L2
SCHEMBL1353519 0.75 HCAR2 (0.36) HCAR2KEAP1NFE2L2
Methacrylic Acid SCHEMBL28832901 0.75 ALDH1A1 (0.38) HCAR2KEAP1NFE2L2ALDH1A1MAPT
SCHEMBL1353520 0.75 HCAR2 (0.36) HCAR2KEAP1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2607394-B1 Adhesive masses with high mole masses and a dense mole mass distribution and process for their preparation TESA AG (DE) 2015-06-03 EP disclosed
US-8846833-B2 Pressure-sensitive adhesives with high molar masses and narrow molar mass distribution and process for preparing them TESA SE (DE) 2014-09-30 US disclosed
US-20130165606-A1 Pressure-Sensitive Adhesives with High Molar Masses and Narrow Molar Mass Distribution and Process for Preparing them TESA SE (DE) 2013-06-27 US disclosed
EP-2607394-A1 Adhesive masses with high mole masses and a dense mole mass distribution and process for their preparation tesa AG (DE) 2013-06-26 EP disclosed