Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 4/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.42 |
| ▸ | BCR | P11274 | 2/20 | 0.42 |
| ▸ | MMP3 | P08254 | 2/20 | 0.41 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | USP7 | Q93009 | 1/20 | 0.40 |
| ▸ | EDNRB | P24530 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29496707 | 0.90 | MEN1 (0.47) | MEN1KMT2AKDM4EESR1HSD17B1 | |
| SCHEMBL918436 | 0.86 | KMT2A (0.61) | MEN1KMT2AKDM4EESR1ESR2 | |
| SCHEMBL573085 | 0.80 | KMT2A (0.47) | MEN1KMT2AKDM4EESR1ESR2 | |
| SCHEMBL23310483 | 0.80 | EDNRB (0.40) | MEN1KMT2AKDM4EKDM1AHDAC6 | |
| SCHEMBL21959118 | 0.80 | EDNRB (0.40) | MEN1KMT2AKDM4EKDM1AHDAC6 | |
| SCHEMBL13805589 | 0.79 | MAPK1 (0.44) | MEN1KMT2AEDNRBEDNRACYP3A4 | |
| SCHEMBL24741894 | 0.79 | EDNRB (0.50) | ESR2EDNRBEDNRACYP3A4PDK2 | |
| SCHEMBL17280984 | 0.78 | USP7 (0.40) | MEN1KMT2AKDM4EESR1HSD17B1 | |
| SCHEMBL27372447 | 0.78 | KDM1A (0.47) | KDM4EMMP3BCL2L1KDM1ACYP3A4 | |
| SCHEMBL3465804 | 0.77 | HSD17B1 (0.46) | MEN1KMT2AESR1HSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2610307-A1 | CONTACT COMPONENT WITH REDUCED SQUEAK NOISE MADE FROM THERMOPLASTIC RESIN COMPOSITION | Techno Polymer Co., Ltd. (JP) | 2013-07-03 | — | — | EP | disclosed |