Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 8/20 | 0.52 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5161 | 0.79 | ALOX5 (0.59) | ALOX5DHODHMEN1KMT2AGAA | |
| SCHEMBL25006 | 0.79 | ALOX5 (0.59) | ALOX5DHODHMEN1KMT2AGAA | |
| SCHEMBL851887 | 0.73 | ALOX5 (0.55) | ALOX5DHODHMEN1KMT2AGAA | |
| Phenoxazine SCHEMBL7862 | 0.70 | ALOX5 (1.00) | ALOX5DHODHMEN1KMT2AGAA | |
| Phenoxazine SCHEMBL29355714 | 0.70 | ALOX5 (1.00) | ALOX5DHODHMEN1KMT2AGAA | |
| Phenoxazine SCHEMBL28844098 | 0.70 | ALOX5 (1.00) | ALOX5DHODHMEN1KMT2AGAA | |
| Phenoxazine SCHEMBL6310178 | 0.70 | ALOX5 (1.00) | ALOX5DHODHMEN1KMT2AGAA | |
| Phenoxazine SCHEMBL25275195 | 0.68 | ALOX5 (0.94) | ALOX5DHODHMEN1KMT2AGAA | |
| Phenoxazine SCHEMBL31267446 | 0.68 | ALOX5 (0.94) | ALOX5DHODHMEN1KMT2AGAA | |
| Phenoxazine SCHEMBL5808288 | 0.68 | ALOX5 (0.94) | ALOX5DHODHMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10472381-B2 | Sialic acid derivatives | REINHARD BROSSMER (DE) | 2019-11-12 | — | — | US | disclosed |
| WO-2018172129-A1 | SIALIC ACID DERIVATIVES WITH C-C TRIPLE BOND, AND PREPARATION THEREOF | PRESCHER HORST (CH) | 2018-09-27 | — | — | WO | disclosed |
| EP-3129390-A1 | SIALIC ACID DERIVATIVES | Brossmer, Reinhard (DE) | 2017-02-15 | — | — | EP | disclosed |
| US-20160362436-A1 | SIALIC ACID DERIVATIVES | BROSSMER REINHARD (DE) | 2016-12-15 | — | — | US | disclosed |
| EP-2797946-B1 | SIALIC ACID DIMERS | BROSSMER REINHARD (DE) | 2016-05-04 | — | — | EP | disclosed |
| US-9260467-B2 | Sialic acid dimers | BROSSMER REINHARD (DE) | 2016-02-16 | — | — | US | disclosed |
| WO-2015128344-A1 | SIALIC ACID DERIVATIVES | BROSSMER REINHARD (DE) | 2015-09-03 | — | — | WO | disclosed |
| EP-2910561-A1 | Sialic acid derivatives | Brossmer, Reinhard (DE) | 2015-08-26 | — | — | EP | disclosed |
| US-20150005245-A1 | Sialic Acid Dimers | BROSSMER REINHARD (DE) | 2015-01-01 | — | — | US | disclosed |
| EP-2797946-A1 | SIALIC ACID DIMERS | Brossmer, Reinhard (DE) | 2014-11-05 | — | — | EP | disclosed |
| WO-2013097942-A1 | SIALIC ACID DIMERS | BROSSMER REINHARD (DE) | 2013-07-04 | — | — | WO | disclosed |
| EP-2610263-A1 | Sialic acid dimers | Brossmer, Reinhard (DE) | 2013-07-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10472381-B2 | Sialic acid derivatives | NEU1, NEU2, NEU3 | ALOX5 995/4885DHODH 2072/4885MEN1 1137/4885 |
| US-20160362436-A1 | SIALIC ACID DERIVATIVES | NEU1, NEU2, NEU3 | ALOX5 997/4885DHODH 2076/4885MEN1 1135/4885 |
| US-20150005245-A1 | Sialic Acid Dimers | SIGLEC9, SIGLEC7, NEU2 | ALOX5 1537/4885DHODH 4157/4885MEN1 2389/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.