Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 12/20 | 0.39 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 14/20 | 0.38 |
| ▸ | SRC | P12931 | 10/20 | 0.38 |
| ▸ | SYK | P43405 | 10/20 | 0.38 |
| ▸ | BRAF | P15056 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15063026 | 0.97 | GSK3A (0.41) | MAPK14MAP3K20GSK3ASRCSYK | |
| SCHEMBL2671367 | 0.91 | MAPK14 (0.40) | MAPK14MAP3K20GSK3ASRCSYK | |
| SCHEMBL1935735 | 0.90 | BRAF (0.47) | MAPK14GSK3ASRCSYKBRAF | |
| SCHEMBL2671034 | 0.89 | GSK3A (0.41) | MAPK14MAP3K20GSK3ASRCSYK | |
| SCHEMBL2671097 | 0.88 | GSK3A (0.48) | MAPK14MAP3K20GSK3ASRCSYK | |
| SCHEMBL1935715 | 0.88 | BRAF (0.45) | MAPK14GSK3ASRCSYKBRAF | |
| SCHEMBL2671828 | 0.85 | GSK3A (0.46) | MAPK14MAP3K20GSK3ASRCSYK | |
| SCHEMBL1936807 | 0.83 | GSK3A (0.44) | MAPK14GSK3ASRCSYKBRAF | |
| SCHEMBL1936023 | 0.83 | BRAF (0.41) | MAPK14MAP3K20GSK3ASRCSYK | |
| SCHEMBL1936142 | 0.81 | BRAF (0.42) | MAPK14GSK3ASRCSYKBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331506-B1 | NOVEL BENZAMIDES, PRODUCTION THEREOF, AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM INT (DE) | 2013-07-03 | — | — | EP | disclosed |