Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.74 |
| ▸ | GAA | P10253 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.63 |
| ▸ | MEN1 | O00255 | 7/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | ACP1 | P24666 | 1/20 | 0.58 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.58 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | STAT1 | P42224 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15063122 | 0.94 | MAPT (0.66) | MAPTGAAKMT2AMEN1ALDH1A1 | |
| SCHEMBL15083819 | 0.94 | MAPT (0.65) | MAPTGAAKMT2AMEN1ALDH1A1 | |
| SCHEMBL18700065 | 0.93 | MAPT (0.64) | MAPTGAAKMT2AMEN1ALDH1A1 | |
| SCHEMBL15489026 | 0.93 | MAPT (0.64) | MAPTGAAKMT2AMEN1ALDH1A1 | |
| SCHEMBL18905633 | 0.93 | MAPT (0.65) | MAPTGAAKMT2AMEN1ALDH1A1 | |
| SCHEMBL15112845 | 0.90 | KMT2A (0.66) | MAPTGAAKMT2AMEN1ALDH1A1 | |
| SCHEMBL18700000 | 0.90 | MAPT (0.61) | MAPTGAAKMT2AMEN1ALDH1A1 | |
| SCHEMBL18700002 | 0.89 | MAPT (0.66) | MAPTGAAKMT2AMEN1ALDH1A1 | |
| SCHEMBL15489025 | 0.87 | MAPT (0.63) | MAPTGAAKMT2AMEN1ALDH1A1 | |
| SCHEMBL18905634 | 0.87 | MAPT (0.60) | MAPTGAAKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3431584-B1 | METHODS FOR FREEZING AN AGGREGATE OF PLURIPOTENT STEM CELL-DERIVED CARDIOMYOCYTES | UNIV KYOTO (JP) | 2023-06-28 | — | — | EP | disclosed |
| EP-3150705-B1 | METHOD FOR INDUCING MYOCARDIAL DIFFERENTIATION OF PLURIPOTENT STEM CELLS USING LOW-MOLECULAR COMPOUND | UNIV KYOTO (JP) | 2019-05-15 | — | — | EP | disclosed |
| EP-2966166-B1 | PROMOTER OF DIFFERENTIATION OF PLURIPOTENT STEM CELL INTO MYOCARDIUM, WHICH COMPRISES EGF RECEPTOR INHIBITOR | UNIV KYOTO (JP) | 2019-04-03 | — | — | EP | disclosed |
| EP-3431584-A1 | FREEZING METHOD FOR AGGREGATES OF PLURIPOTENT STEM CELL-DERIVED MYOCARDIAL CELLS | Kyoto University (JP) | 2019-01-23 | — | — | EP | disclosed |
| EP-2808383-B1 | METHOD FOR INDUCING CARDIAC DIFFERENTIATION OF PLURIPOTENT STEM CELL | UNIV KYOTO (JP) | 2018-07-25 | — | — | EP | disclosed |
| EP-2808383-B1 | METHOD FOR INDUCING CARDIAC DIFFERENTIATION OF PLURIPOTENT STEM CELL | UNIV KYOTO (JP) | 2018-07-25 | — | — | EP | disclosed |
| EP-2610249-B1 | PLURIPOTENT STEM CELL CARDIOMYOCYTE DIFFERENTIATION-PROMOTING AGENT | UNIV KYOTO (JP) | 2017-10-11 | — | — | EP | disclosed |
| EP-2610249-B1 | PLURIPOTENT STEM CELL CARDIOMYOCYTE DIFFERENTIATION-PROMOTING AGENT | UNIV KYOTO (JP) | 2017-10-11 | — | — | EP | disclosed |
| US-20170152485-A1 | Method for Inducing Cardiac Differentiation of Pluripotent Stem Cell with Low-Molecular Compounds | KYOTO UNIVERSITY (JP) | 2017-06-01 | — | — | US | disclosed |
| US-20170152485-A1 | Method for Inducing Cardiac Differentiation of Pluripotent Stem Cell with Low-Molecular Compounds | KYOTO UNIVERSITY (JP) | 2017-06-01 | — | — | US | disclosed |
| EP-2808383-A1 | METHOD FOR INDUCING DIFFERENTIATION OF PLURIPOTENT STEM CELL INTO CARDIAC MUSCLE | Kyoto University (JP) | 2014-12-03 | — | — | EP | disclosed |
| US-20140127807-A1 | Method for Promoting Differentiation of Pluripotent Stem Cells into Cardiac Muscle Cells | KYOTO UNIVERSITY (JP) | 2014-05-08 | — | — | US | disclosed |
| US-8658425-B2 | Method for promoting differentiation of pluripotent stem cells into cardiac muscle cells | KYOTO UNIVERSITY (JP) | 2014-02-25 | — | — | US | disclosed |
| US-8658425-B2 | Method for promoting differentiation of pluripotent stem cells into cardiac muscle cells | KYOTO UNIVERSITY (JP) | 2014-02-25 | — | — | US | disclosed |
| US-8658425-B2 | Method for promoting differentiation of pluripotent stem cells into cardiac muscle cells | KYOTO UNIVERSITY (JP) | 2014-02-25 | — | — | US | disclosed |
| US-20130183753-A1 | METHOD FOR PROMOTING DIFFERENTIATION OF PLURIPOTENT STEM CELLS INTO CARDIAC MUSCLE CELLS | KYOTO UNIVERSITY (JP) | 2013-07-18 | — | — | US | disclosed |
| US-20130183753-A1 | METHOD FOR PROMOTING DIFFERENTIATION OF PLURIPOTENT STEM CELLS INTO CARDIAC MUSCLE CELLS | KYOTO UNIVERSITY (JP) | 2013-07-18 | — | — | US | disclosed |
| US-20130183753-A1 | METHOD FOR PROMOTING DIFFERENTIATION OF PLURIPOTENT STEM CELLS INTO CARDIAC MUSCLE CELLS | KYOTO UNIVERSITY (JP) | 2013-07-18 | — | — | US | disclosed |
| EP-2610249-A1 | PLURIPOTENT STEM CELL CARDIOMYOCYTE DIFFERENTIATION-PROMOTING AGENT | Kyoto University (JP) | 2013-07-03 | — | — | EP | disclosed |
| EP-2610249-A1 | PLURIPOTENT STEM CELL CARDIOMYOCYTE DIFFERENTIATION-PROMOTING AGENT | Kyoto University (JP) | 2013-07-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130183753-A1 | METHOD FOR PROMOTING DIFFERENTIATION OF PLURIPOTENT STEM CELLS INTO CARDIAC MUSCLE CELLS | TNNI3, MYLK2, TNNT2 | MAPT 4471/4885GAA 2914/4885KMT2A 3036/4885 |
| US-20140127807-A1 | Method for Promoting Differentiation of Pluripotent Stem Cells into Cardiac Muscle Cells | TNNI3, MYLK2, TNNT2 | MAPT 4439/4885GAA 2721/4885KMT2A 2992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.