Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL5180701 | 1.00 | TSHR (0.51) | TSHRACHEFFAR1HDAC3HDAC1 | |
| Adipic Acid SCHEMBL15167368 | 0.98 | TSHR (0.53) | TSHRACHEFFAR1HDAC3HDAC1 | |
| Sebacic Acid SCHEMBL9311898 | 0.96 | HDAC11 (0.52) | TSHRACHEFFAR1HDAC3HDAC1 | |
| Hexanoate SCHEMBL29016066 | 0.90 | AKR1B1 (0.59) | TSHRFFAR1HDAC11MAPTKMT2A | |
| Adipic Acid SCHEMBL28584893 | 0.90 | TSHR (0.51) | TSHRACHEFFAR1HDAC3HDAC1 | |
| Dodecanoate SCHEMBL28418541 | 0.89 | GPR84 (0.61) | TSHRFFAR1HDAC11MAPTKMT2A | |
| Sebacic Acid SCHEMBL28395117 | 0.89 | HDAC3 (0.50) | TSHRACHEFFAR1HDAC3HDAC1 | |
| Azelaic Acid SCHEMBL28393484 | 0.89 | HDAC3 (0.50) | TSHRACHEFFAR1HDAC3HDAC1 | |
| M-Xylene SCHEMBL3694363 | 0.89 | PARP1 (0.47) | TSHRACHEFFAR1HDAC3HDAC1 | |
| Glutarate SCHEMBL28401701 | 0.86 | TSHR (0.51) | TSHRACHEFFAR1HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113613901-A | Multilayer structure and package | 三菱化学株式会社 | 2021-11-05 | — | — | CN | disclosed |
| EP-2301998-B1 | PROCESS FOR PRODUCING EVOH COMPOSITE MATERIAL | NIPPON SYNTHETIC CHEM IND (JP) | 2014-11-26 | — | — | EP | disclosed |
| US-8722785-B2 | Process for producing EVOH composite | THE NIPPON SYNTHETIC CHEMICAL INDUSTRY CO., LTD. (JP) | 2014-05-13 | — | — | US | disclosed |
| US-20110178222-A1 | PROCESS FOR PRODUCING EVOH COMPOSITE | THE NIPPON SYNTHETIC CHEMICAL INDUSTRY CO., LTD., (JP) | 2011-07-21 | — | — | US | disclosed |
| EP-2301998-A1 | PROCESS FOR PRODUCING EVOH COMPOSITE MATERIAL | The Nippon Synthetic Chemical Industry Co., Ltd. (JP) | 2011-03-30 | — | — | EP | disclosed |