Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 5/20 | 0.37 |
| ▸ | DRD3 | P35462 | 4/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.34 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25887140 | 0.98 | DAO (0.39) | DAOKDM1AMAOBDRD3KCNH2 | |
| SCHEMBL25887137 | 0.86 | MAOB (0.43) | DAOKDM1AMAOBMEN1KMT2A | |
| SCHEMBL26501053 | 0.82 | DAO (0.52) | DAOKDM1AMAOBDRD3KCNH2 | |
| SCHEMBL6657810 | 0.82 | DAO (0.52) | DAOKDM1AMAOBDRD3KCNH2 | |
| SCHEMBL15066016 | 0.82 | DAO (0.39) | DAOKDM1AMAOBDRD3KCNH2 | |
| SCHEMBL12359045 | 0.81 | MEN1 (0.37) | DRD3MEN1KMT2AACHEGRIN2B | |
| SCHEMBL18623662 | 0.80 | DAO (0.38) | DAOKDM1AMAOBDRD3KCNH2 | |
| SCHEMBL152808 | 0.79 | DAO (0.40) | DAOKDM1AMAOBDRD3KCNH2 | |
| SCHEMBL12790350 | 0.79 | MEN1 (0.44) | MEN1KMT2AHRH3 | |
| SCHEMBL13397441 | 0.79 | MEN1 (0.44) | MEN1KMT2AACHEGRIN2BHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9644066-B2 | Cyclic amine compounds, compositions, and polyurethane foams made therefrom | DOW GLOBAL TECHNOLOGIES LLC (US) | 2017-05-09 | — | — | US | disclosed |
| EP-2797902-B1 | COMPOSITIONS CONTAINING CYCLIC AMINE COMPOUNDS, AND POLYURETHANE FOAMS MADE THEREFROM | DOW GLOBAL TECHNOLOGIES LLC (US) | 2017-04-26 | — | — | EP | disclosed |
| US-20150005404-A1 | CYCLIC AMINE COMPOUNDS, COMPOSITIONS, AND POLYURETHANE FOAMS MADE THEREFROM | DOW GLOBAL TECHNOLOGIES LLC | 2015-01-01 | — | — | US | disclosed |
| EP-2797902-A2 | CYCLIC AMINE COMPOUNDS, COMPOSITIONS, AND POLYURETHANE FOAMS MADE THEREFROM | Dow Global Technologies LLC (US) | 2014-11-05 | — | — | EP | disclosed |
| WO-2013102097-A2 | CYCLIC AMINE COMPOUNDS, COMPOSITIONS, AND POLYURETHANE FOAMS MADE THEREFROM | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-07-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150005404-A1 | CYCLIC AMINE COMPOUNDS, COMPOSITIONS, AND POLYURETHANE FOAMS MADE THEREFROM | PUF60, UFM1, POLM | DAO 241/4885KDM1A 1019/4885MAOB 95/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.