Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12790350 | 0.95 | MEN1 (0.44) | MEN1KMT2ACARM1PRMT6PRMT8 | |
| SCHEMBL12790351 | 0.93 | MEN1 (0.42) | MEN1KMT2ACARM1PRMT6PRMT8 | |
| SCHEMBL13397349 | 0.86 | HRH3 (0.41) | MEN1KMT2ASIGMAR1HRH3 | |
| SCHEMBL12359045 | 0.84 | MEN1 (0.37) | MEN1KMT2ASIGMAR1HRH3ACHE | |
| SCHEMBL13397474 | 0.82 | HRH3 (0.46) | MEN1KMT2ACARM1PRMT6PRMT8 | |
| SCHEMBL13397351 | 0.80 | HRH3 (0.50) | MEN1KMT2AHRH3 | |
| SCHEMBL945818 | 0.80 | SMN1; SMN2 (0.41) | MEN1KMT2ASIGMAR1POLB | |
| SCHEMBL42491 | 0.80 | MEN1 (0.34) | MEN1KMT2AACHEGRIN2B | |
| SCHEMBL12790371 | 0.80 | ALDH1A1 (0.42) | SIGMAR1HRH3ACHE | |
| SCHEMBL25887140 | 0.80 | DAO (0.39) | MEN1KMT2ASIGMAR1HRH3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100104659-A1 | BENZOPYRANOPYRAZOLES | 4SC AG (DE) | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100104659-A1 | BENZOPYRANOPYRAZOLES | BAX, BCL2, BAD | MEN1 4734/4885KMT2A 3784/4885CARM1 1315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.