Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 13/20 | 0.69 |
| ▸ | SLC6A3 | Q01959 | 13/20 | 0.69 |
| ▸ | SLC6A4 | P31645 | 12/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NQO1 | P15559 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15065338 | 0.93 | SLC6A2 (0.67) | SLC6A2SLC6A3SLC6A4KDM4ERECQL | |
| SCHEMBL15065557 | 0.92 | SLC6A2 (0.68) | SLC6A2SLC6A3SLC6A4KDM4ERECQL | |
| SCHEMBL15065497 | 0.92 | SLC6A2 (0.66) | SLC6A2SLC6A3SLC6A4KDM4ERECQL | |
| SCHEMBL15066384 | 0.91 | SLC6A2 (0.69) | SLC6A2SLC6A3SLC6A4KDM4ERECQL | |
| SCHEMBL15066381 | 0.89 | SLC6A3 (0.55) | SLC6A2SLC6A3SLC6A4KDM4ERECQL | |
| SCHEMBL15066416 | 0.87 | SLC6A3 (0.53) | SLC6A2SLC6A3SLC6A4KDM4ECHRM2 | |
| SCHEMBL15065898 | 0.87 | SLC6A3 (0.53) | SLC6A2SLC6A3SLC6A4CHRM2CHRM1 | |
| SCHEMBL15065924 | 0.86 | SLC6A2 (0.52) | SLC6A2SLC6A3SLC6A4KDM4ECHRM2 | |
| SCHEMBL15065528 | 0.85 | SLC6A3 (0.52) | SLC6A2SLC6A3SLC6A4CHRM2CHRM1 | |
| SCHEMBL15065471 | 0.84 | SLC6A2 (0.67) | SLC6A2SLC6A3SLC6A4KDM4ERECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2797870-A1 | COMPOSITIONS, SYNTHESIS, AND METHODS OF USING PHENYLCYCLOALKYLMETHYLAMINE DERIVATIVES | Reviva Pharmaceuticals, Inc. (US) | 2014-11-05 | — | — | EP | disclosed |
| WO-2013102195-A1 | COMPOSITIONS, SYNTHESIS, AND METHODS OF USING PHENYLCYCLOALKYLMETHYLAMINE DERIVATIVES | REVIVA PHARMACEUTICALS, INC. (US) | 2013-07-04 | — | — | WO | disclosed |