SCHEMBL15067459

SCHEMBL15067459

OC[CH]Cc1ccccc1Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 5/20 0.46
PNMT P11086 1/20 0.46
TAAR1 Q96RJ0 6/20 0.44
LMNA P02545 3/20 0.44
HTT P42858 3/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
PKM P14618 1/20 0.44
RAB9A P51151 2/20 0.42
NPC1 O15118 1/20 0.42
ALDH1A1 P00352 1/20 0.41
HTR3E A5X5Y0 1/20 0.40
HTR3B O95264 1/20 0.40
HTR3A P46098 1/20 0.40
HTR3D Q70Z44 1/20 0.40
HTR3C Q8WXA8 1/20 0.40
HPGD P15428 1/20 0.40
TSHR P16473 1/20 0.39
MEN1 O00255 1/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9318738 0.83 PNMT (0.52) IDO1PNMTTAAR1SMN1; SMN2ALDH1A1
SCHEMBL10989621 0.81 TAAR1 (0.47) IDO1PNMTTAAR1LMNAHTT
SCHEMBL10989622 0.81 TAAR1 (0.47) IDO1PNMTTAAR1LMNAHTT
SCHEMBL3789553 0.78 PNMT (0.58) IDO1PNMTTAAR1LMNAHTT
SCHEMBL4995355 0.75 IDO1 (0.50) IDO1LMNAHTTSMN1; SMN2RAB9A
SCHEMBL575127 0.75 IDO1 (0.52) IDO1PNMTTAAR1LMNAHTT
SCHEMBL16168614 0.75 IDO1 (0.52) IDO1PNMTTAAR1LMNAHTT
SCHEMBL15066706 0.74 TAAR1 (0.43) IDO1TAAR1CYP2D6CYP2C9CYP2C19
SCHEMBL15067218 0.74 TAAR1 (0.45) IDO1TAAR1LMNARAB9AALDH1A1
SCHEMBL96359 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2970112-A1 PHENYL CARBAMATE COMPOUND AND A COMPOSITION FOR PREVENTING OR TREATING A MEMORY LOSS-RELATED DISEASE COMPRISING THE SAME Bio-Pharm Solutions Co., Ltd. (KR) 2016-01-20 EP disclosed
EP-2797879-A1 PHENYL CARBAMATE COMPOUNDS FOR USE IN ALLEVIATING OR TREATING PAIN AND NEUROPATHIC PAIN Bio-Pharm Solutions Co., Ltd. (KR) 2014-11-05 EP disclosed
WO-2014142549-A1 PHENYL CARBAMATE COMPOUND AND A COMPOSITION FOR PREVENTING OR TREATING A MEMORY LOSS-RELATED DISEASE COMPRISING THE SAME BIO-PHARM SOLUTIONS CO., LTD. (KR) 2014-09-18 WO disclosed
WO-2013100567-A1 PHENYL CARBAMATE COMPOUNDS FOR USE IN ALLEVIATING OR TREATING PAIN AND NEUROPATHIC PAIN BIO-PHARM SOLUTIONS CO., LTD. (KR) 2013-07-04 WO disclosed