Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 19/20 | 1.00 |
| ▸ | PPARD | Q03181 | 16/20 | 1.00 |
| ▸ | PPARG | P37231 | 14/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16243191 | 0.89 | PPARG (0.80) | PPARAPPARDPPARG | |
| SCHEMBL15066833 | 0.86 | PPARA (0.76) | PPARAPPARDPPARG | |
| SCHEMBL15067047 | 0.84 | PPARG (0.72) | PPARAPPARDPPARG | |
| SCHEMBL15067511 | 0.83 | PPARD (1.00) | PPARAPPARDPPARG | |
| SCHEMBL15067483 | 0.80 | PPARD (0.76) | PPARAPPARDPPARG | |
| SCHEMBL15068170 | 0.80 | PPARD (0.76) | PPARAPPARDPPARG | |
| SCHEMBL15067393 | 0.80 | PPARD (1.00) | PPARAPPARDPPARG | |
| SCHEMBL15067564 | 0.79 | PPARA (1.00) | PPARAPPARDPPARG | |
| SCHEMBL16242816 | 0.78 | PPARG (0.64) | PPARAPPARDPPARG | |
| SCHEMBL16242996 | 0.77 | PPARA (0.78) | PPARAPPARDPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115073-B2 | 1,3-diphenylpropane derivatives, preparations and uses thereof | GENFIT (FR) | 2015-08-25 | — | — | US | claimed |
| EP-2811992-A1 | 1,3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES THEREOF | Genfit (FR) | 2014-12-17 | — | — | EP | claimed |
| US-20140350112-A1 | 1,3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES THEREOF | GENFIT (FR) | 2014-11-27 | — | — | US | claimed |
| WO-2013098374-A1 | 1,3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES THEREOF | GENFIT (FR) | 2013-07-04 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140350112-A1 | 1,3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES THEREOF | PPARD, PPARA, PPARG | PPARA 2/4885PPARD 1/4885PPARG 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.