Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.80 |
| ▸ | PPARA | Q07869 | 11/20 | 0.80 |
| ▸ | PPARD | Q03181 | 9/20 | 0.80 |
| ▸ | FBP1 | P09467 | 4/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.32 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.31 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16242816 | 0.89 | PPARG (0.64) | PPARGPPARAPPARDFBP1NTRK1 | |
| SCHEMBL15067759 | 0.89 | PPARA (1.00) | PPARGPPARAPPARD | |
| SCHEMBL16242849 | 0.86 | PPARG (0.61) | PPARGPPARAPPARDCYP3A4 | |
| SCHEMBL16242925 | 0.84 | PPARA (0.80) | PPARGPPARAPPARDFBP1ABCB11 | |
| SCHEMBL16243254 | 0.82 | PPARD (0.61) | PPARGPPARAPPARD | |
| SCHEMBL16243117 | 0.82 | PPARD (0.61) | PPARGPPARAPPARD | |
| SCHEMBL16243187 | 0.81 | PPARD (0.79) | PPARGPPARAPPARD | |
| SCHEMBL16242804 | 0.81 | PPARA (0.78) | PPARGPPARAPPARDFBP1ABCB11 | |
| SCHEMBL16243193 | 0.80 | PPARA (0.63) | PPARGPPARAPPARDABCB11CYP1A2 | |
| SCHEMBL16242939 | 0.79 | PPARA (0.79) | PPARGPPARAPPARDFBP1ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115073-B2 | 1,3-diphenylpropane derivatives, preparations and uses thereof | GENFIT (FR) | 2015-08-25 | — | — | US | disclosed |
| US-20140350112-A1 | 1,3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES THEREOF | GENFIT (FR) | 2014-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140350112-A1 | 1,3-DIPHENYLPROPANE DERIVATIVES, PREPARATIONS AND USES THEREOF | PPARD, PPARA, PPARG | PPARG 3/4885PPARA 2/4885PPARD 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.