Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30422597 | 0.83 | POLB (0.40) | POLBALDH1A1CYP2A6KMT2AMEN1 | |
| SCHEMBL29723440 | 0.75 | TP53 (0.37) | POLBALDH1A1CYP2A6KMT2AMEN1 | |
| SCHEMBL4263305 | 0.73 | TSHR (0.41) | POLBALDH1A1CYP2A6KDM4EHPGD | |
| SCHEMBL22175514 | 0.73 | MEN1 (0.49) | POLBALDH1A1CYP2A6KMT2AMEN1 | |
| SCHEMBL10311218 | 0.71 | HTR5A (0.37) | POLBALDH1A1CYP2A6CYP1A2TSHR | |
| SCHEMBL15311418 | 0.68 | HTR5A (0.38) | RECQL | |
| SCHEMBL12290744 | 0.68 | TNKS (0.34) | ALDH1A1CDK5NOX1 | |
| SCHEMBL7906187 | 0.68 | MEN1 (0.44) | POLBALDH1A1CYP2A6KMT2AMEN1 | |
| SCHEMBL2258047 | 0.67 | BACE1 (0.33) | — | |
| SCHEMBL15119748 | 0.67 | PDK2 (0.46) | POLBALDH1A1CYP2A6KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115634295-A | Near-infrared fluorescence/magnetic resonance dual-mode probe and preparation method and application thereof | 中国科学院深圳先进技术研究院 | 2023-01-24 | — | — | CN | disclosed |
| WO-2020047477-A1 | CATIONIC COMPOUNDS FOR DELIVERY OF NUCLEIC ACIDS | CITY OF HOPE (US) | 2020-03-05 | — | — | WO | disclosed |
| WO-2014200872-A9 | PHARMACEUTICAL COMPOUNDS TARGETED BY MIF AFFINITY-TETHERED MOIETIES | RJS BIOLOGICS LLC (US) | 2015-02-05 | — | — | WO | disclosed |
| WO-2014200872-A1 | PHARMACEUTICAL COMPOUNDS TARGETED BY MIF AFFINITY-TETHERED MOIETIES | RJS BIOLOGICS LLC (US) | 2014-12-18 | — | — | WO | disclosed |
| US-8702815-B2 | Cyanoborate, fluoroalkylphosphate, fluoroalkylborate or imide dyes | MERCK PATENT GMBH (DE) | 2014-04-22 | — | — | US | disclosed |
| EP-2292700-B1 | Cyanoborate dyes | MERCK PATENT GMBH (DE) | 2011-11-02 | — | — | EP | disclosed |
| US-20110190480-A1 | CYANOBORATE, FLUOROALKYLPHOSPHATE, FLUOROALKYLBORATE OR IMIDE DYES | IGNATYEV NIKOLAI MYKOLA | 2011-08-04 | — | — | US | disclosed |
| US-7939644-B2 | cationic dyes used for coloring plastics, fibers, leather and paper, for the preparation of flexographic printing inks, as ball-point pen pastes, as stamp inks, for use in data acquisition systems, reprography, in ink microfilters, in photogalvanics, laser technology and the photo industry | MERCK PATENT GMBH (DE) | 2011-05-10 | — | — | US | disclosed |
| EP-2292700-A1 | Cyanoborate dyes | Merck Patent GmbH (DE) | 2011-03-09 | — | — | EP | disclosed |
| EP-1660591-B1 | CATIONIC FLUOROALKYL-PHOSPHATE DYES | MERCK PATENT GMBH (DE) | 2010-10-27 | — | — | EP | disclosed |
| US-20080275224-A1 | Cyanoborate, Fluoroalkylphosphate, Fluoroalkylborate or Imide Dyes | MERCK PATENT GMBH (DE) | 2008-11-06 | — | — | US | disclosed |
| EP-1660591-A1 | CYANOBORATE, FLUOROALKYL PHOSPHATE, FLUOROALKYL BORATE OR IMIDE DYES | MERCK PATENT GmbH (DE) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005021661-A1 | CYANOBORATE, FLUOROALKYL PHOSPHATE, FLUOROALKYL BORATE OR IMIDE DYES | MERCK PATENT GMBH (DE) | 2005-03-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110190480-A1 | CYANOBORATE, FLUOROALKYLPHOSPHATE, FLUOROALKYLBORATE OR IMIDE DYES | ZAP70, MYLK3, KIT | POLB 1510/4885ALDH1A1 1799/4885CYP2A6 4543/4885 |
| US-20080275224-A1 | Cyanoborate, Fluoroalkylphosphate, Fluoroalkylborate or Imide Dyes | ZAP70, MYLK3, KIT | POLB 1510/4885ALDH1A1 1799/4885CYP2A6 4543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.