Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12126541 | 0.95 | — | — | |
| SCHEMBL17022241 | 0.81 | MCL1 (0.41) | TSHRHSD17B10RECQLHDAC1HDAC10 | |
| SCHEMBL13912379 | 0.81 | ALDH1A1 (0.35) | TSHRHSD17B10RECQLHDAC1HDAC10 | |
| SCHEMBL12661037 | 0.80 | KDM4E (0.40) | TSHRRECQL | |
| SCHEMBL23289286 | 0.78 | MEN1 (0.48) | RECQL | |
| SCHEMBL21440852 | 0.78 | CA1 (0.37) | RECQL | |
| SCHEMBL21440819 | 0.78 | CA1 (0.37) | RECQL | |
| SCHEMBL20887524 | 0.78 | CA1 (0.37) | RECQL | |
| SCHEMBL17574393 | 0.78 | MEN1 (0.48) | RECQL | |
| SCHEMBL1493216 | 0.78 | ALDH1A1 (0.41) | HSD17B10RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013132094-A1 | PEPTIDES BASED TARGETING OF THE PLATELET DERIVED GROWTH FACTOR RECEPTOR BETA (PDGFRβ) AND CD276 | UNIVERSITÄTSKLINIKUM HEIDELBERG (DE) | 2013-09-12 | — | — | WO | disclosed |
| WO-2013093099-A1 | STABILIZATION OF PEPTIDIC RADIOPHARMACEUTICALS USING URIC ACID OR DERIVATIVES THEREOF | PIRAMAL IMAGING SA (DE) | 2013-06-27 | — | — | WO | disclosed |