⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15664805 | 0.85 | — | — | |
| SCHEMBL744752 | 0.82 | CYP1A1 (0.61) | — | |
| SCHEMBL6833539 | 0.77 | APP (0.50) | — | |
| SCHEMBL5550636 | 0.77 | CHRNB2 (0.57) | — | |
| SCHEMBL7054960 | 0.76 | — | — | |
| SCHEMBL30310124 | 0.76 | CHRNB2 (0.61) | — | |
| SCHEMBL2614843 | 0.76 | CHRNB2 (0.61) | — | |
| SCHEMBL12282882 | 0.76 | CHRNB2 (0.47) | — | |
| SCHEMBL6764164 | 0.76 | CHRNB2 (0.47) | — | |
| SCHEMBL14154914 | 0.76 | MAP4K4 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1304325-A1 | 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-23 | — | — | EP | claimed |
| US-12606541-B2 | PPARg modulators and methods of use | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2026-04-21 | — | — | US | disclosed |
| CN-119569648-A | Novel energetic compound and preparation method thereof | 信阳师范学院 | 2025-03-07 | — | — | CN | disclosed |
| US-20230062861-A1 | PPARg MODULATORS AND METHODS OF USE | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2023-03-02 | — | — | US | disclosed |
| EP-3442955-B1 | SELECTIVE D3 DOPAMINE RECEPTOR AGONISTS AND METHODS OF THEIR USE | US HEALTH (US) | 2021-09-29 | — | — | EP | disclosed |
| US-10618926-B2 | Process for making phosphoramidate protected nucleoside compounds | MERCK SHARP & DOHME (US) | 2020-04-14 | — | — | US | disclosed |
| US-10000507-B2 | Furo- and thieno-pyridine carboxamide compounds useful as pim kinase inhibitors | INCYTE CORPORATION (US) | 2018-06-19 | — | — | US | disclosed |
| US-20180111954-A1 | PROCESS FOR MAKING PHOSPHORAMIDATE PROTECTED NUCLEOSIDE COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2018-04-26 | — | — | US | disclosed |
| WO-2017181004-A1 | SELECTIVE D3 DOPAMINE RECEPTOR AGONISTS AND METHODS OF THEIR USE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2017-10-19 | — | — | WO | disclosed |
| US-20170275327-A1 | SUBSTITUTED PHOSPHORAMIDATE COMPOUNDS AND USES THEREOF | MERCK SHARP & DOHME LLC | 2017-09-28 | — | — | US | disclosed |
| CN-1907969-A | Benzoylpyridine derivative or its salt, disinfectant containing the same as active ingredient method for producing the same and intermediate for producing the same | ISHIHARA SANGYO KAISHA (JP) | 2007-02-07 | — | — | CN | disclosed |
| CN-1635877-A | Treatment of affective disorders by the combined action of a nicotinic receptor agonist and a monoaminergic substance | NEUROSEARCH AS (DK) | 2005-07-06 | — | — | CN | disclosed |
| WO-2004069256-A1 | 2-CYANOPYRROLOPYRIMIDINES AND PHARMACEUTICAL USES THEREOF | NOVARTIS AG (CH) | 2004-08-19 | — | — | WO | disclosed |
| US-20040092508-A1 | Treatment of affective disorders by the combined action of a nicotinic receptor agonist and a monoaminergic substance | ANIONA APS (DK) | 2004-05-13 | — | — | US | disclosed |
| EP-1358177-A2 | TREATMENT OF AFFECTIVE DISORDERS BY THE COMBINED ACTION OF A NICOTINIC RECEPTOR AGONIST AND A MONOAMINERGIC SUBSTANCE | NeuroSearch A/S (DK) | 2003-11-05 | — | — | EP | disclosed |
| CN-1440389-A | Benzoylpyridine derivative or its salt, fungicide containing it as active ingredient, its production method and intermediate for producing it | ISHIHARA SANGYO KAISHA (JP) | 2003-09-03 | — | — | CN | disclosed |
| EP-1304325-A1 | 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-23 | — | — | EP | disclosed |
| WO-2003020721-A1 | PYRROLO PYRIMIDINES AS AGENTS FOR THE INHIBITION OF CYSTEIN PROTEASES | NOVARTIS AG (CH) | 2003-03-13 | — | — | WO | disclosed |
| WO-2002030405-A2 | TREATMENT OF AFFECTIVE DISORDERS BY THE COMBINED ACTION OF A NICOTINIC RECEPTOR AGONIST AND A MONOAMINERGIC SUBSTANCE | NEUROSEARCH A/S (DK) | 2002-04-18 | — | — | WO | disclosed |
| US-4713080-A | OXIDATIVE COLORING | WELLA AKTIENGESELLSCHAFT (DE) | 1987-12-15 | — | — | US | disclosed |