Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA4 | P22748 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18249449 | 0.87 | POLB (0.49) | OPRK1CA12CA1CA2CA4 | |
| SCHEMBL14968453 | 0.84 | POLB (0.46) | OPRK1POLBHDAC3HDAC4HDAC1 | |
| SCHEMBL4400652 | 0.83 | OPRK1 (0.46) | OPRK1CA12CA1CA2CA4 | |
| SCHEMBL4401002 | 0.83 | OPRK1 (0.46) | OPRK1CA12CA1CA2CA4 | |
| SCHEMBL13643851 | 0.82 | OPRK1 (0.49) | OPRK1CA12CA1CA2CA4 | |
| SCHEMBL13892196 | 0.81 | POLB (0.49) | POLBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL13643840 | 0.80 | OPRK1 (0.52) | OPRK1CA12CA1CA2CA4 | |
| SCHEMBL13643871 | 0.80 | OPRK1 (0.52) | OPRK1CA12CA1CA2CA4 | |
| SCHEMBL4397934 | 0.80 | OPRK1 (0.45) | OPRK1CA12CA1CA2CA4 | |
| SCHEMBL13643847 | 0.80 | OPRK1 (0.45) | OPRK1CA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013093720-A2 | ANTI-DIABETIC COMPOUNDS | PFIZER INC. (US) | 2013-06-27 | — | — | WO | disclosed |