Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 10/20 | 0.44 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31522 | 0.89 | F2RL1 (0.44) | HPGDF2RL1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL15071150 | 0.85 | HPGD (0.49) | HPGDF2RL1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL15071148 | 0.85 | HPGD (0.49) | HPGDF2RL1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL31560 | 0.75 | F2RL1 (0.63) | HPGDF2RL1ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL15071129 | 0.74 | HPGD (0.50) | HPGDF2RL1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL15071149 | 0.74 | HPGD (0.58) | HPGDF2RL1ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL15071141 | 0.74 | F2RL1 (0.61) | HPGDF2RL1ALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL15071137 | 0.72 | F2RL1 (0.59) | HPGDF2RL1ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL15050221 | 0.70 | F2RL1 (0.53) | HPGDF2RL1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL15071135 | 0.69 | F2RL1 (0.58) | HPGDF2RL1ALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130165652-A1 | NOVEL HETEROCYCLIC COMPOUND, AND COMPOSITION FOR TREATING INFLAMMATORY DISEASES USING SAME | NEOPHARM CO.,LTD. (KR) | 2013-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165652-A1 | NOVEL HETEROCYCLIC COMPOUND, AND COMPOSITION FOR TREATING INFLAMMATORY DISEASES USING SAME | F2RL1, F2R, FPR2 | HPGD 80/4885F2RL1 1/4885ALDH1A1 3710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.