SCHEMBL150750

SCHEMBL150750

COc1cc(OC)nc(Cl)n1

nearest known ligand 0.52

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.52
HTT P42858 1/20 0.52
SMN1; SMN2 Q16637 3/20 0.48
LMNA P02545 2/20 0.48
L3MBTL1 Q9Y468 2/20 0.45
CYP1A2 P05177 1/20 0.43
KDM4E B2RXH2 3/20 0.41
PDE2A O00408 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
ALOX15 P16050 1/20 0.37
TSHR P16473 1/20 0.37
MAPT P10636 1/20 0.36
HPGD P15428 1/20 0.36
RECQL P46063 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trimethylammonium SCHEMBL9045332 0.93 ALDH1A1 (0.47) ALDH1A1HTTSMN1; SMN2LMNAL3MBTL1
SCHEMBL2339978 0.87 ALDH1A1 (0.47) ALDH1A1HTTSMN1; SMN2LMNAL3MBTL1
SCHEMBL11834614 0.85 ALDH1A1 (0.46) ALDH1A1HTTSMN1; SMN2LMNAL3MBTL1
SCHEMBL2131428 0.85 ALDH1A1 (0.70) ALDH1A1HTTSMN1; SMN2LMNACYP1A2
SCHEMBL12101919 0.84 ALDH1A1 (0.44) ALDH1A1HTTSMN1; SMN2LMNAL3MBTL1
SCHEMBL9433456 0.83 ALDH1A1 (0.41) ALDH1A1HTTSMN1; SMN2LMNAL3MBTL1
SCHEMBL27903823 0.82 CYP1A2 (0.49) ALDH1A1HTTSMN1; SMN2LMNACYP1A2
SCHEMBL12549038 0.80 HRH4 (0.44) ALDH1A1HTTSMN1; SMN2LMNAL3MBTL1
SCHEMBL14225685 0.80 KMT2A (0.57) ALDH1A1HTTSMN1; SMN2LMNAL3MBTL1
SCHEMBL22576253 0.80 ALDH1A1 (0.42) ALDH1A1HTTSMN1; SMN2LMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 530 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118994030-A Preparation method of pyrimidine derivative 4, 6-dichloro-2-pyrimidine carboxylic acid methyl ester 上海毕臣生化科技有限公司 2024-11-22 CN claimed
CN-111689909-A Preparation method of herbicide pyrithiobac-sodium 江苏慧博生物科技有限公司 2020-09-22 CN claimed
CN-107759528-B Synthesis method of 2-chloro-4, 6-dimethoxypyrimidine 营口营新化工科技有限公司 2020-05-19 CN claimed
CN-1467206-A Preparation method of 2-chloro-4, 6-dimethoxypyrimidine 金坛希望化工有限公司 2004-01-14 CN claimed
JP-3232881-A None JP disclosed
JP-3264567-A None JP disclosed
JP-4342575-A None JP disclosed
JP-3200784-A None JP disclosed
EP-4729127-A2 BCL6 INHIBITORS Cancer Research Technology Limited (GB) 2026-04-22 EP disclosed
US-20260102762-A1 TRI-(ADAMANTYL)PHOSPHINES AND APPLICATIONS THEREOF THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2026-04-16 US disclosed
US-20260042776-A1 BCL6 INHIBITORS CANCER RESEARCH TECH LTD (GB) 2026-02-12 US disclosed
US-12539508-B2 Tri-(adamantyl) phosphines and applications thereof THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2026-02-03 US disclosed
EP-0374839-A1 2-(4,6-Dimethoxy-2-pyrimidinyloxy)benzaldoximes, preparation processes thereof, herbicides containing the same, and herbicidal compositions containing the same along with other active ingredients MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-06-27 EP disclosed
US-4931087-A Picolinic acid derivatives and herbicidal compositions KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1990-06-05 US disclosed
US-4906285-A Pyrimidine derivatives and herbicidal method and compositions KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1990-03-06 US disclosed
US-4900352-A 2-Phenoxypyimidine derivative and herbicidal composition KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1990-02-13 US disclosed
EP-0321846-A2 Pyrimidine derivatives, processes for their production, and herbicidal method and compositions KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1989-06-28 EP disclosed
US-4832729-A Picolinic acid derivatives and herbicidal compositions KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1989-05-23 US disclosed
EP-0249707-A1 Picolinic acid derivatives and herbicidal compositions KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1987-12-23 EP disclosed
EP-0249708-A1 2-Phenoxypyrimidine derivative and herbicidal compositions KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1987-12-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12539508-B2 Tri-(adamantyl) phosphines and applications thereof OTC, AOC3, ICOSLG ALDH1A1 943/4885HTT 4349/4885SMN1; SMN2 3637/4885
US-20260102762-A1 TRI-(ADAMANTYL)PHOSPHINES AND APPLICATIONS THEREOF PTMS, TEC, CD2 ALDH1A1 2483/4885HTT 4198/4885SMN1; SMN2 4342/4885
US-20260042776-A1 BCL6 INHIBITORS BCL6, BCL6B, BCL9 ALDH1A1 3510/4885HTT 3878/4885SMN1; SMN2 3903/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.