Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.39 |
| ▸ | AKT1 | P31749 | 2/20 | 0.39 |
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | SRD5A1 | P18405 | 7/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19030425 | 0.86 | AKT1 (0.41) | TRPV1AKT1MAP3K14PPARAPPARG | |
| SCHEMBL15075028 | 0.83 | TRPV1 (0.39) | TRPV1MAP3K14PPARAPPARGPPARD | |
| SCHEMBL23422992 | 0.80 | KDM1A (0.40) | MAP3K14PPARAPPARGPPARDKDM1A | |
| SCHEMBL27471598 | 0.78 | KDM1A (0.41) | MAP3K14PPARAPPARGPPARDKDM1A | |
| SCHEMBL15075096 | 0.77 | TRPV1 (0.40) | TRPV1MAP3K14PPARAPPARGPPARD | |
| SCHEMBL19030772 | 0.74 | MAP3K14 (0.43) | TRPV1MAP3K14PPARAPPARGPPARD | |
| SCHEMBL19030382 | 0.74 | PPARA (0.40) | TRPV1PPARAPPARGPPARD | |
| SCHEMBL10346652 | 0.72 | AKT1 (0.54) | AKT1PPARAPPARGPPARDBCHE | |
| SCHEMBL10346642 | 0.70 | AKT1 (0.46) | AKT1PPARAPPARGPPARDBCHE | |
| SCHEMBL10346909 | 0.70 | AKT1 (0.46) | AKT1BCHESRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013096226-A1 | TRPV1 ANTAGONISTS | ABBVIE INC. (US) | 2013-06-27 | — | — | WO | disclosed |