Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 10/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | MAP3K14 | Q99558 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15075099 | 0.83 | TRPV1 (0.39) | TRPV1KDM1AMAP3K14PPARGPPARD | |
| SCHEMBL15074995 | 0.82 | HTR2C (0.47) | TRPV1KDM1APPARGHTR2CDRD2 | |
| SCHEMBL15075010 | 0.76 | SIGMAR1 (0.45) | TRPV1HTR2CDRD2HTR2A | |
| SCHEMBL23422992 | 0.75 | KDM1A (0.40) | KDM1AMAP3K14PPARGPPARDPPARA | |
| SCHEMBL15075094 | 0.72 | EPHX2 (0.43) | TRPV1KDM1AHTR2CDRD2HTR2A | |
| SCHEMBL15075096 | 0.72 | TRPV1 (0.40) | TRPV1KDM1AMAP3K14PPARGPPARD | |
| SCHEMBL19030425 | 0.72 | AKT1 (0.41) | TRPV1KDM1AMAP3K14PPARGPPARD | |
| SCHEMBL15075026 | 0.70 | TRPV1 (0.39) | TRPV1HTR2CHTR2A | |
| SCHEMBL2317910 | 0.69 | MAOB (0.44) | TRPV1 | |
| SCHEMBL3321108 | 0.68 | TRPV1 (0.44) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013096226-A1 | TRPV1 ANTAGONISTS | ABBVIE INC. (US) | 2013-06-27 | — | — | WO | disclosed |