Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAPDH | P04406 | 1/20 | 0.35 |
| ▸ | HRAS | P01112 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SYNJ2 | O15056 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15075322 | 0.90 | ALDH1A1 (0.43) | ALDH1A1POLBGAAMAPK1NPSR1 | |
| SCHEMBL15574918 | 0.90 | ALDH1A1 (0.43) | ALDH1A1POLBGAAMAPK1NPSR1 | |
| SCHEMBL19535619 | 0.88 | ALDH1A1 (0.41) | ALDH1A1POLBGAAMAPK1NPSR1 | |
| SCHEMBL19535621 | 0.88 | ALDH1A1 (0.41) | ALDH1A1POLBGAAMAPK1NPSR1 | |
| SCHEMBL21007946 | 0.88 | ALDH1A1 (0.41) | ALDH1A1POLBGAAMAPK1NPSR1 | |
| SCHEMBL19535620 | 0.88 | ALDH1A1 (0.41) | ALDH1A1POLBGAAMAPK1NPSR1 | |
| SCHEMBL14821346 | 0.88 | ALDH1A1 (0.40) | ALDH1A1POLBGAAMAPK1NPSR1 | |
| SCHEMBL14820863 | 0.88 | ALDH1A1 (0.40) | ALDH1A1POLBGAAMAPK1NPSR1 | |
| SCHEMBL15075168 | 0.87 | ALDH1A1 (0.41) | ALDH1A1POLBGAAMAPK1NPSR1 | |
| SCHEMBL18671847 | 0.85 | ALDH1A1 (0.42) | ALDH1A1POLBGAAMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013096680-A1 | SUBSTITUTED PHOSPHOROTHIOATE NUCLEOTIDE ANALOGS | ALIOS BIOPHARMA, INC. (US) | 2013-06-27 | — | — | WO | disclosed |