Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | BUB1 | O43683 | 5/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | GCGR | P47871 | 3/20 | 0.38 |
| ▸ | CSF1R | P07333 | 4/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | GIPR | P48546 | 2/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15075433 | 0.91 | ADORA2A (0.40) | ADORA2A | |
| SCHEMBL15055475 | 0.79 | BUB1 (0.43) | BUB1CNR2 | |
| SCHEMBL15056092 | 0.78 | NPC1 (0.37) | ADORA2ABUB1PDE2AGCGRCNR2 | |
| SCHEMBL16992786 | 0.77 | PDE2A (0.45) | ADORA2APDE2ACNR2 | |
| SCHEMBL18899545 | 0.74 | BUB1 (0.52) | BUB1 | |
| SCHEMBL15075439 | 0.73 | SMN1; SMN2 (0.40) | ADORA2A | |
| SCHEMBL15060027 | 0.73 | BUB1 (0.55) | BUB1 | |
| SCHEMBL16731507 | 0.72 | BUB1 (0.47) | BUB1 | |
| SCHEMBL14843903 | 0.71 | BUB1 (0.68) | BUB1CNR2 | |
| SCHEMBL15075435 | 0.70 | PDE2A (0.41) | PDE2AGCGRCNR2GIPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2794596-B1 | SUBSTITUTED BENZYLPYRAZOLES | BAYER IP GMBH (DE) | 2017-05-31 | — | — | EP | disclosed |
| EP-2794596-B1 | SUBSTITUTED BENZYLPYRAZOLES | BAYER IP GMBH (DE) | 2017-05-31 | — | — | EP | disclosed |
| US-9643953-B2 | Substituted benzylpyrazoles | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-05-09 | — | — | US | disclosed |
| US-9643953-B2 | Substituted benzylpyrazoles | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-05-09 | — | — | US | disclosed |
| US-9643953-B2 | Substituted benzylpyrazoles | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-05-09 | — | — | US | disclosed |
| US-9422268-B2 | — | — | 2016-08-23 | — | — | US | disclosed |
| US-9422268-B2 | — | — | 2016-08-23 | — | — | US | disclosed |
| US-9422268-B2 | — | — | 2016-08-23 | — | — | US | disclosed |
| US-20140315934-A1 | SUBSTITUTED BENZYLPYRAZOLES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-10-23 | — | — | US | disclosed |
| US-20140315934-A1 | SUBSTITUTED BENZYLPYRAZOLES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-10-23 | — | — | US | disclosed |
| US-20140315934-A1 | SUBSTITUTED BENZYLPYRAZOLES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-10-23 | — | — | US | disclosed |
| WO-2013092512-A1 | SUBSTITUTED BENZYLPYRAZOLES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-06-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140315934-A1 | SUBSTITUTED BENZYLPYRAZOLES | CYP3A43, CYP3A7, ABCB1 | ADORA2A 2822/4885BUB1 2233/4885PDE2A 561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.