Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17860653 | 0.87 | PDE3A (0.49) | PDE4DPDE3ASLC29A1LMNATHRB | |
| SCHEMBL17860926 | 0.87 | PDE3A (0.49) | PDE4DPDE3ASLC29A1LMNATHRB | |
| SCHEMBL15070482 | 0.87 | PDE3A (0.49) | PDE4DPDE3ASLC29A1LMNATHRB | |
| SCHEMBL15075448 | 0.81 | LMNA (0.37) | PDE4DPDE3ASLC29A1LMNATHRB | |
| SCHEMBL19861748 | 0.80 | SLC28A1 (0.47) | SLC29A1 | |
| SCHEMBL15070515 | 0.80 | SLC28A1 (0.47) | SLC29A1 | |
| SCHEMBL17860639 | 0.80 | SLC28A1 (0.47) | SLC29A1 | |
| SCHEMBL17359832 | 0.80 | LMNA (0.36) | PDE4DPDE3ASLC29A1LMNATHRB | |
| SCHEMBL15075449 | 0.80 | LMNA (0.36) | PDE4DPDE3ASLC29A1LMNATHRB | |
| SCHEMBL16492179 | 0.79 | LMNA (0.35) | PDE4DPDE3ASLC29A1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013142525-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | ALIOS BIOPHARMA, INC. (US) | 2013-09-26 | — | — | WO | disclosed |
| WO-2013096679-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | ALIOS BIOPHARMA, INC. (US) | 2013-06-27 | — | — | WO | disclosed |