Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | STING1 | Q86WV6 | 8/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | HINT1 | P49773 | 1/20 | 0.45 |
| ▸ | NT5E | P21589 | 1/20 | 0.45 |
| ▸ | KRAS | P01116 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25400949 | 1.00 | ADORA3 (0.51) | ADORA3STING1PDE3BPDE3AHINT1 | |
| SCHEMBL15070714 | 1.00 | ADORA3 (0.51) | ADORA3STING1PDE3BPDE3AHINT1 | |
| SCHEMBL25580314 | 0.92 | ADORA3 (0.47) | ADORA3STING1PDE3BPDE3AHINT1 | |
| SCHEMBL17359805 | 0.92 | ADORA3 (0.52) | ADORA3STING1PDE3BPDE3AHINT1 | |
| SCHEMBL16373915 | 0.92 | ADORA3 (0.52) | ADORA3STING1PDE3BPDE3AHINT1 | |
| SCHEMBL25397152 | 0.91 | ADORA3 (0.52) | ADORA3STING1PDE3BPDE3AHINT1 | |
| SCHEMBL17358545 | 0.90 | ADORA3 (0.47) | ADORA3STING1PDE3BPDE3AHINT1 | |
| SCHEMBL25401067 | 0.90 | ADORA3 (0.51) | ADORA3STING1PDE3BPDE3AHINT1 | |
| SCHEMBL15070633 | 0.90 | ADORA3 (0.51) | ADORA3STING1PDE3BPDE3AHINT1 | |
| SCHEMBL25400020 | 0.90 | ADORA3 (0.55) | ADORA3STING1PDE3BPDE3AHINT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013096679-A1 | SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF | ALIOS BIOPHARMA, INC. (US) | 2013-06-27 | — | — | WO | disclosed |