Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15076578 | 0.83 | MEN1 (0.48) | SMN1; SMN2ALDH1A1HTR2BNPC1RAB9A | |
| SCHEMBL15076577 | 0.81 | KMT2A (0.50) | SMN1; SMN2ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL15076572 | 0.80 | MEN1 (0.53) | SMN1; SMN2ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL15276981 | 0.80 | HTR2B (0.51) | ALDH1A1HTR2BTDP1KMT2ALMNA | |
| SCHEMBL15076596 | 0.79 | KMT2A (0.52) | SMN1; SMN2ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL23677225 | 0.78 | SMN1; SMN2 (0.70) | SMN1; SMN2ALDH1A1HTR2BNPC1RAB9A | |
| SCHEMBL15076369 | 0.78 | MEN1 (0.49) | SMN1; SMN2ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL15076595 | 0.77 | MEN1 (0.51) | SMN1; SMN2ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL15076575 | 0.77 | RAB9A (0.46) | SMN1; SMN2ALDH1A1NPC1RAB9AMEN1 | |
| SCHEMBL15076583 | 0.76 | TP53 (0.47) | SMN1; SMN2ALDH1A1NPC1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013096744-A1 | HEPATITIS B ANTIVIRAL AGENTS | NOVIRA THERAPEUTICS, INC. (US) | 2013-06-27 | — | — | WO | disclosed |