Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | SMO | Q99835 | 3/20 | 0.55 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.52 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | USP28 | Q96RU2 | 2/20 | 0.48 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.48 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15076618 | 0.86 | SMO (0.60) | LMNASMOAVPR2GPR27CYP2C19 | |
| SCHEMBL15076553 | 0.81 | TP53 (0.53) | LMNACYP2C19ENPP2ALDH1A1KMT2A | |
| SCHEMBL17465703 | 0.79 | KMT2A (0.59) | LMNASMOAVPR2GPR27CYP2C19 | |
| SCHEMBL15076614 | 0.79 | LMNA (0.55) | LMNACYP2C19ENPP2ALDH1A1MEN1 | |
| SCHEMBL15277035 | 0.79 | TP53 (0.73) | LMNAPOLBMAPT | |
| SCHEMBL15076539 | 0.79 | LMNA (0.58) | LMNAENPP2ALDH1A1KMT2ALPAR1 | |
| SCHEMBL16768729 | 0.78 | TP53 (0.49) | LMNAENPP2ALDH1A1MEN1KMT2A | |
| SCHEMBL15076526 | 0.78 | TP53 (0.57) | LMNACYP2C19ENPP2POLBLPAR1 | |
| SCHEMBL15076501 | 0.78 | CYP3A4 (0.62) | LMNACYP2C19ENPP2ALDH1A1KMT2A | |
| SCHEMBL15277040 | 0.78 | TP53 (0.72) | LMNAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013096744-A1 | HEPATITIS B ANTIVIRAL AGENTS | NOVIRA THERAPEUTICS, INC. (US) | 2013-06-27 | — | — | WO | disclosed |