Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 18/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28124623 | 0.78 | PIK3C3 (0.51) | PIK3C3PIP5K1CPIK3CA | |
| SCHEMBL15051235 | 0.76 | PIK3C3 (0.43) | PIK3C3GSK3BMAPK14 | |
| SCHEMBL15051156 | 0.76 | PIK3C3 (0.42) | PIK3C3GSK3BMAPK14PIP5K1CPIK3CA | |
| SCHEMBL15050809 | 0.72 | PIK3C3 (0.52) | PIK3C3MAPK14 | |
| SCHEMBL19736124 | 0.72 | PIK3C3 (0.57) | PIK3C3 | |
| SCHEMBL953124 | 0.71 | MAPK14 (0.47) | PIK3C3MAPK14PIP5K1CPIK3CA | |
| SCHEMBL953912 | 0.71 | MAPK14 (0.42) | PIK3C3GSK3BMAPK14 | |
| SCHEMBL12852676 | 0.70 | ROCK2 (0.41) | PIK3C3MAPK14 | |
| SCHEMBL19706510 | 0.70 | PIK3C3 (0.62) | PIK3C3 | |
| SCHEMBL16850488 | 0.69 | GSK3B (0.44) | PIK3C3GSK3BMAPK14PIP5K1CPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013096637-A1 | HETEROARYLS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2013-06-27 | — | — | WO | disclosed |