SCHEMBL1507731

SCHEMBL1507731

NC1C(n2cnc3cncnc32)O[C@H](CO)[C@H]1O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ADORA3 P0DMS8 4/20 0.64
▸ POLB P06746 1/20 0.64
▸ ADA P00813 1/20 0.55
▸ DNMT3B Q9UBC3 1/20 0.52
▸ DPP4 P27487 1/20 0.51
▸ MEN1 O00255 1/20 0.51
▸ SLC28A1 O00337 1/20 0.51
▸ MAP3K7 O43318 1/20 0.51
▸ SLC28A2 O43868 1/20 0.51
▸ GAPDH P04406 1/20 0.51
▸ MAPK1 P28482 1/20 0.51
▸ ADORA2A P29274 1/20 0.51
▸ ADORA2B P29275 1/20 0.51
▸ ADORA1 P30542 1/20 0.51
▸ STAT6 P42226 1/20 0.51
▸ PI4KA P42356 1/20 0.51
▸ KMT2A Q03164 1/20 0.51
▸ SMN1; SMN2 Q16637 1/20 0.51
▸ PI4K2B Q8TCG2 1/20 0.51
▸ DOT1L Q8TEK3 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25424615 1.00 ADORA3 (0.64) ADORA3POLBADADNMT3BDPP4
SCHEMBL5489450 1.00 ADORA3 (0.64) ADORA3POLBADADNMT3BDPP4
SCHEMBL5489442 1.00 ADORA3 (0.64) ADORA3POLBADADNMT3BDPP4
SCHEMBL14580421 1.00 ADORA3 (0.64) ADORA3POLBADADNMT3BDPP4
SCHEMBL14580423 0.90 ADORA3 (0.64) ADORA3POLBADADNMT3BDPP4
Nebularine SCHEMBL9644429 0.89 ADA (0.65) ADORA3ADADNMT3BDPP4MEN1
Nebularine SCHEMBL745560 0.89 ADA (0.65) ADORA3ADADNMT3BDPP4MEN1
Nebularine SCHEMBL10666450 0.89 ADA (0.65) ADORA3ADADNMT3BDPP4MEN1
Nebularine SCHEMBL742475 0.89 ADA (0.65) ADORA3ADADNMT3BDPP4MEN1
Nebularine SCHEMBL29362246 0.89 ADA (0.65) ADORA3ADADNMT3BDPP4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2352846-B1 RNA DETECTION METHOD RIBOXX GMBH (DE) 2015-01-07 — — EP disclosed
EP-2463385-B1 Kit for RNA detection RIBOXX GMBH (DE) 2014-08-27 — — EP disclosed
EP-2673376-A1 METHOD FOR THE DETECTION OF POLYNUCLEOTIDE SEQUENCES RiboxX GmbH (DE) 2013-12-18 — — EP disclosed
WO-2012107537-A1 METHOD FOR THE DETECTION OF POLYNUCLEOTIDE SEQUENCES RIBOXX GMBH (DE) 2012-08-16 — — WO disclosed
EP-2463385-A1 Kit for RNA detection RiboxX GmbH (DE) 2012-06-13 — — EP disclosed
US-20110212451-A1 RNA DETECTION METHOD RIBOXX GMBH (DE) 2011-09-01 — — US disclosed
EP-2352846-A1 RNA DETECTION METHOD Riboxx GmbH (DE) 2011-08-10 — — EP disclosed
EP-2298935-A1 Methods for detection of a target nucleic acid sequence Hologic Inc. (US) 2011-03-23 — — EP disclosed
US-7846661-B2 Methods of detecting an amplified nucleic acid HOLOGIC, INC. (US) 2010-12-07 — — US disclosed
US-7824859-B2 Methods for detection of a target nucleic acid by forming a cleavage structure using an RNA polymerase CYTYC CORPORATION (US) 2010-11-02 — — US disclosed
WO-2002031200-A1 METHODS FOR DETECTION OF A TARGET NUCLEIC ACID USING A PROBE COMPRISING SECONDARY STRUCTURE STRATAGENE (US) 2002-04-18 — — WO disclosed
US-6350580-B1 GENERATING A SIGNAL INDICATIVE OF A TARGET NUCLEIC ACID IN A SAMPLE BY INCUBATING THE NUCLEIC ACID WITH A PROBE THAT CHANGES ITS SECONDARY STRUCTURE UPON BINDING OF A PROBE TO THE TARGET AND CLEAVING A CLEAVAGE STRUCTURE WITH A NUCLEASE STRATAGENE 2002-02-26 — — US disclosed
WO-2001032922-A2 METHODS FOR DETECTION OF A TARGET NUCLEIC ACID SEQUENCE STRATAGENE (US) 2001-05-10 — — WO disclosed
US-6214979-B1 Homogeneous assay system ROCHE MOLECULAR SYSTEMS 2001-04-10 — — US disclosed
EP-0543942-B1 HOMOGENEOUS ASSAY SYSTEM HOFFMANN LA ROCHE (CH) 2001-01-24 — — EP disclosed
EP-0919565-A2 Labeled oligonucleotides F. HOFFMANN-LA ROCHE AG (CH) 1999-06-02 — — EP disclosed
US-5804375-A PAIR OF NUCLEOTIDE PRIMERS AND LABELED OLIGONUCLEOTIDE ROCHE MOLECULAR SYSTEMS, INC. (US) 1998-09-08 — — US disclosed
US-5487972-A POLYMERASE CHAIN REACTION AMPLIFICATION HOFFMANN-LA ROCHE INC. (US) 1996-01-30 — — US disclosed
EP-0543942-A1 HOMOGENEOUS ASSAY SYSTEM F. HOFFMANN-LA ROCHE AG (CH) 1993-06-02 — — EP disclosed
WO-1992002638-A1 HOMOGENEOUS ASSAY SYSTEM F. HOFFMANN-LA ROCHE AG (CH) 1992-02-20 — — WO disclosed
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