Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 7/20 | 0.53 |
| ▸ | HPRT1 | P00492 | 12/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7262127 | 0.93 | CYP3A4 (0.62) | CYP3A4HPRT1CYP2D6 | |
| SCHEMBL97295 | 0.88 | HPRT1 (0.64) | CYP3A4HPRT1 | |
| SCHEMBL15078156 | 0.87 | POLB (0.55) | CYP3A4HPRT1CYP2D6 | |
| SCHEMBL15078154 | 0.87 | POLB (0.55) | CYP3A4HPRT1CYP2D6 | |
| SCHEMBL20997459 | 0.82 | HPRT1 (0.43) | CYP3A4HPRT1 | |
| SCHEMBL4715034 | 0.81 | HPRT1 (0.70) | CYP3A4HPRT1 | |
| SCHEMBL4713142 | 0.81 | HPRT1 (0.70) | CYP3A4HPRT1 | |
| SCHEMBL172846 | 0.81 | HPRT1 (0.70) | CYP3A4HPRT1 | |
| SCHEMBL97265 | 0.81 | CYP3A4 (0.62) | CYP3A4CYP2D6 | |
| SCHEMBL17194157 | 0.80 | HPRT1 (0.64) | CYP3A4HPRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013095684-A1 | GUANINE ANALOGS AS TELOMERASE SUBSTRATES AND TELOMERE LENGTH AFFECTORS | GERON CORPORATION (US) | 2013-06-27 | — | — | WO | disclosed |